CAS 72301-78-1

Zinviroxime

Description:

Zinviroxime, with the CAS number 72301-78-1, is a chemical compound that has been studied primarily for its potential applications in the field of medicinal chemistry, particularly as an antiviral agent. It is characterized by its unique molecular structure, which includes specific functional groups that contribute to its biological activity. Zinviroxime has been noted for its ability to inhibit certain viral enzymes, thereby interfering with the replication of viruses. The compound is typically evaluated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), which are crucial for determining its efficacy and safety in therapeutic applications. Additionally, Zinviroxime may exhibit varying solubility and stability profiles, influencing its formulation and delivery methods. As research continues, the compound's potential side effects and interactions with other drugs are also important considerations in its development as a therapeutic agent. Overall, Zinviroxime represents a significant area of interest in the ongoing search for effective antiviral treatments.

Formula: C₁₇H₁₈N₄O₃S

InChI: InChI=1/C17H18N4O3S/c1-11(2)25(23,24)21-15-10-13(8-9-14(15)19-17(21)18)16(20-22)12-6-4-3-5-7-12/h3-11,22H,1-2H3,(H2,18,19)/b20-16-

SMILES: CC(C)S(=O)(=O)n1c2cc(ccc2[nH]c1=N)/C(=N\O)/c1ccccc1

Synonyms:

• Viroxime
• (Z)-{2-amino-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-6-yl}(phenyl)methanone oxime

Zinviroxime

Controlled Product

CAS: 72301-78-1

Applications Zinviroxime is the (Z)-isomer of Enviroxime (E559600). Zinviroxime is a benzimidazole derivative that inhibits rhinovirus multiplication.
References De Long, D.C., et al.: J. Infect. Dis., 141, 87 (1980), Wikel, J.H., et al.: J. Med. Chem., 23, 368 (1980), Phillpotts, R.J., et al.: Lancet, 1, 1342 (1981), Haden, F.G., et al.: Antimicrob. Agents Chemother., 21, 892 (1982),

Formula: C₁₇H₁₈N₄O₃S

Color and Shape: Neat

Molecular weight: 358.41

Ref: TR-Z465300

Zinviroxime

CAS: 72301-78-1

Formula: C₁₇H₁₈N₄O₃S

Molecular weight: 358.41

Ref: ST-EA-CP-E299001

Zinviroxime

CAS: 72301-78-1

Zinviroxime is a potent and selective inhibitor of the ion channel TRPV1. It blocks the activity of this receptor and prevents the release of inflammatory mediators such as calcitonin gene-related peptide, substance P, and bradykinin. Zinviroxime has been shown to inhibit the binding of these mediators to their receptors on cells in culture. This inhibition causes pain relief in animal models. Zinviroxime also inhibits the activation of TRPV1 by capsaicin, an activator of TRPV1. The molecular weight for zinviroxime is 836 Daltons and its CAS number is 72301-78-1.

Formula: C₁₇H₁₈N₄O₃S

Purity: Min. 95%

Molecular weight: 358.4 g/mol

Ref: 3D-XCA30178