CAS 7232-21-5

Metoclopramide hydrochloride

Description:

Metoclopramide hydrochloride is a medication primarily used as an antiemetic and gastroprokinetic agent. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula that reflects its complex structure, which includes a substituted benzamide. The substance acts by blocking dopamine receptors in the central nervous system and enhancing gastrointestinal motility, making it effective in treating nausea, vomiting, and certain gastric disorders. Metoclopramide hydrochloride is typically administered orally or intravenously, and its pharmacological effects can be attributed to its ability to increase the rate of gastric emptying and improve the tone of the lower esophageal sphincter. Common side effects may include drowsiness, fatigue, and gastrointestinal disturbances. Due to its potential for serious side effects, including tardive dyskinesia with long-term use, it is important for healthcare providers to monitor patients closely. Overall, Metoclopramide hydrochloride is a valuable therapeutic agent in managing various gastrointestinal conditions.

Formula: C₁₄H₂₂ClN₃O₂·ClH

InChI: InChI=1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H

InChI key: InChIKey=RVFUNJWWXKCWNS-UHFFFAOYSA-N

SMILES: C(NCCN(CC)CC)(=O)C1=C(OC)C=C(N)C(Cl)=C1.Cl

Synonyms:

• 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide monohydrochloride
• 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride
• 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride (1:1)
• 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride
• 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride hydrate
• 4-amino-5-chloro-N-[2-(diéthylamino)éthyl]-2-méthoxybenzamide chlorhydrate
• 54143-57-6
• Ahr 3070-C
• Ami-metoclopramide
• Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride (9CI)
• Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1)
• Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochloride
• Ccris 7142
• Cerucal
• Clopra
• Maxolon
• Metoclopramide hcl
• Metoclopramide monohydrochloride
• Metoclopramide-Hakim
• Metozolv
• Metozolv ODT
• Metpamid
• Mexeron
• Nsc 354467
• Paspertin
• Perinorm
• Plazilin
• Primperan
• Primperan (tablet)
• Reglan
• Reglan ODT
• Rimetin
• Telperane
• Tserulan
• Unii-W1792A2Rvd
• o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-, monohydrochloride
• Metoclopramide hydrochloride

Metoclopramide

CAS: 364-62-5, 7232-21-5

Formula: C₁₄H₂₂ClN₃O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 299.80

Ref: 3B-M2218

Metoclopramide hydrochloride

CAS: 7232-21-5

5-HT3 serotonin antagonist; D2 dopamine antagonist

Formula: C₁₄H₂₂ClN₃O₂•HCl

Molecular weight: 336.26

Ref: 02-J61545

Metoclopramide hydrochloride

CAS: 7232-21-5

Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.

Formula: C₁₄H₂₂ClN₃O₂·HCl

Purity: 99.99%

Color and Shape: White To Off-White Powder

Molecular weight: 336.26

Ref: TM-T1069

Metoclopramide hydrochloride

CAS: 7232-21-5

Metoclopramide hydrochloride

Purity: ≥98%

Molecular weight: 336.26g/mol

Ref: 54-BUP15642

Metoclopramide Hydrochloride

CAS: 7232-21-5

Metoclopramide Hydrochloride

Purity: 99%

Molecular weight: 336.26g/mol

Ref: 54-OR1028296

Metoclopramide hydrochloride

CAS: 7232-21-5

Formula: C₁₄H₂₂ClN₃O₂·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder or crystalline powder

Molecular weight: 336.26

Ref: 7W-GP6221

Metoclopramide hydrochloride 100 µg/mL in Acetonitrile

CAS: 7232-21-5

Formula: C₁₄H₂₂ClN₃O₂·ClH

Color and Shape: Single Solution

Molecular weight: 336.26

Ref: 04-A15165000AL-100

Metoclopramide hydrochloride

Controlled Product

CAS: 7232-21-5

Formula: C₁₄H₂₂ClN₃O₂·ClH

Color and Shape: Neat

Molecular weight: 336.26

Ref: 04-C15165000

Metoclopramide Hydrochloride

Controlled Product

CAS: 7232-21-5

Applications Metoclopramide Hydrochloride is a signal transducing dopamine D2 receptor antagonist. Antiemetic.
References 1. Fliri, A. et al.: J Med Chem. 2009 Dec 24;52(24):8038-46.2. Mahajan, H. et al.: Drug Deliv. 2010 Jan;17(1):19-27

Formula: C₁₄H₂₂ClN₃O₂·ClH

Color and Shape: Neat

Molecular weight: 336.26

Ref: TR-M338685