CAS 7232-21-5: Metoclopramide hydrochloride
Description:Metoclopramide hydrochloride is a medication primarily used as an antiemetic and gastroprokinetic agent. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula that reflects its complex structure, which includes a substituted benzamide. The substance acts by blocking dopamine receptors in the central nervous system and enhancing gastrointestinal motility, making it effective in treating nausea, vomiting, and certain gastric disorders. Metoclopramide hydrochloride is typically administered orally or intravenously, and its pharmacological effects can be attributed to its ability to increase the rate of gastric emptying and improve the tone of the lower esophageal sphincter. Common side effects may include drowsiness, fatigue, and gastrointestinal disturbances. Due to its potential for serious side effects, including tardive dyskinesia with long-term use, it is important for healthcare providers to monitor patients closely. Overall, Metoclopramide hydrochloride is a valuable therapeutic agent in managing various gastrointestinal conditions.
Formula:C14H22ClN3O2·ClH
InChI:InChI=1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H
InChI key:InChIKey=RVFUNJWWXKCWNS-UHFFFAOYSA-N
SMILES:Cl.O=C(NCCN(CC)CC)C1=CC(Cl)=C(N)C=C1OC
- Synonyms:
- 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide monohydrochloride
- 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride
- 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride (1:1)
- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride
- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride hydrate
- 4-amino-5-chloro-N-[2-(diéthylamino)éthyl]-2-méthoxybenzamide chlorhydrate
- 54143-57-6
- Ahr 3070-C
- Ami-metoclopramide
- Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride (9CI)
- See more synonyms
- Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1)
- Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochloride
- Ccris 7142
- Cerucal
- Clopra
- Maxolon
- Metoclopramide hcl
- Metoclopramide monohydrochloride
- Metoclopramide-Hakim
- Metozolv
- Metozolv ODT
- Metpamid
- Mexeron
- Nsc 354467
- Paspertin
- Perinorm
- Plazilin
- Primperan
- Primperan (tablet)
- Reglan
- Reglan ODT
- Rimetin
- Telperane
- Tserulan
- Unii-W1792A2Rvd
- o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-, monohydrochloride
- Metoclopramide hydrochloride
- Metoclopramide hydrochloride monohydrate