CAS 7236-57-9

1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one

Description:

1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one, with the CAS number 7236-57-9, is a nucleoside analog that exhibits structural features characteristic of both nucleosides and pyrimidine derivatives. This compound contains a 2-deoxy-pentofuranosyl moiety, which is a sugar component commonly found in DNA, linked to a pyrimidinone structure that includes a thioxo group, contributing to its potential biological activity. The presence of the methyl group at the 5-position of the pyrimidine ring may influence its pharmacological properties, including its interaction with biological targets such as enzymes or receptors. This compound has garnered interest in medicinal chemistry for its potential antiviral or anticancer properties, as many nucleoside analogs are designed to interfere with nucleic acid synthesis. Its solubility, stability, and reactivity can vary based on environmental conditions, making it a subject of study in drug development and biochemical research.

Formula: C₁₀H₁₄N₂O₄S

InChI: InChI=1/C10H14N2O4S/c1-5-3-12(10(15)11-9(5)17)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1

Synonyms:

• 1-(2-deoxypentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
• Thymidine, 4-thio-

4-Thiothymidine

CAS: 7236-57-9

4-Thiothymidine

Purity: ≥95%

Molecular weight: 258.29g/mol

Ref: 54-BUP11778

4-Thiothymidine

CAS: 7236-57-9

Formula: C₁₀H₁₄N₂O₄S

Purity: ≥ 98.0%

Color and Shape: Off-white to yellow powder

Molecular weight: 258.3

Ref: 7W-GN0818

4-Thiothymidine

CAS: 7236-57-9

4-Thiothymidine is a Nucleoside Derivative - Thio-nucleoside, 5-Modified pyrimidine nucleoside.

Formula: C₁₀H₁₄N₂O₄S

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 258.29

Ref: TM-TNU0977

4-Thiothymidine

Controlled Product

CAS: 7236-57-9

Formula: C₁₀H₁₄N₂O₄S

Color and Shape: Neat

Molecular weight: 258.29

Ref: TR-T375285

4-Thiothymidine

CAS: 7236-57-9

4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.

Formula: C₁₀H₁₄N₂O₄S

Purity: Min. 98 Area-%

Color and Shape: Yellow Powder

Molecular weight: 258.3 g/mol

Ref: 3D-NT06341

4-Thiothymidine

CAS: 7236-57-9

Purity: 98%

Molecular weight: 258.07

Ref: 10-F555358