CAS 72447-64-4

p-Hydroxyfenbendazole

Description:

p-Hydroxyfenbendazole, with the CAS number 72447-64-4, is a chemical compound that belongs to the class of benzimidazole derivatives. It is primarily recognized for its use as an anthelmintic agent, effective against a variety of parasitic infections in animals. The compound features a hydroxyl group (-OH) at the para position of the phenyl ring, which contributes to its biological activity. p-Hydroxyfenbendazole exhibits moderate solubility in water and is more soluble in organic solvents, which influences its absorption and distribution in biological systems. Its mechanism of action involves the inhibition of microtubule formation in parasites, leading to their immobilization and eventual death. The compound is generally considered to have a favorable safety profile when used as directed in veterinary medicine. Additionally, it is important to handle p-Hydroxyfenbendazole with care, following appropriate safety guidelines, as with any chemical substance.

Formula: C₁₅H₁₃N₃O₃S

InChI: InChI=1S/C15H13N3O3S/c1-21-15(20)18-14-16-12-7-6-11(8-13(12)17-14)22-10-4-2-9(19)3-5-10/h2-8,19H,1H3,(H2,16,17,18,20)

InChI key: InChIKey=KFNQNAKZKBFJAZ-UHFFFAOYSA-N

SMILES: N(C(OC)=O)C=1NC=2C(N1)=CC=C(SC3=CC=C(O)C=C3)C2

Synonyms:

• Carbamic acid, [5-[(4-hydroxyphenyl)thio]-1H-benzimidazol-2-yl]-, methyl ester
• HOE 2542
• p-Hydroxyfenbendazole
• Carbamic acid, N-[6-[(4-hydroxyphenyl)thio]-1H-benzimidazol-2-yl]-, methyl ester