CAS 72448-59-0

2',5'-Dideoxyinosine

CAS: 72448-59-0

2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.

Formula: C₁₀H₁₂N₄O₃

Purity: Min. 95%

Molecular weight: 236.23 g/mol

Ref: 3D-ND08407