CAS 72479-26-6

Fenticonazole

Description:

Fenticonazole is an antifungal agent primarily used in the treatment of various fungal infections, particularly those affecting the skin and mucous membranes. It belongs to the class of imidazole derivatives and exhibits broad-spectrum antifungal activity against a range of pathogens, including dermatophytes, yeasts, and some molds. Fenticonazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. This compound is typically formulated as a topical cream or vaginal suppository, making it suitable for localized treatment. In terms of physical properties, fenticonazole is generally characterized by its white to off-white crystalline appearance and is soluble in organic solvents. Its pharmacokinetics indicate limited systemic absorption when applied topically, which minimizes potential side effects. Overall, fenticonazole is valued for its efficacy, safety profile, and convenience in treating superficial fungal infections.

Formula: C₂₄H₂₀Cl₂N₂OS

InChI: InChI=1/C24H20Cl2N2OS/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20/h1-14,17,24H,15-16H2

InChI key: InChIKey=ZCJYUTQZBAIHBS-UHFFFAOYSA-N

SMILES: C(CN1C=CN=C1)(OCC2=CC=C(SC3=CC=CC=C3)C=C2)C4=C(Cl)C=C(Cl)C=C4

Synonyms:

• 1-(2-(2,4-Dichlorophenyl)-2-((4-(phenylthio)benzyl)oxy)ethyl)-1H-imidazole
• 1-[2-(2,4-Dichlorophenyl)-2-[[4-(Phenylthio)Phenyl]Methoxy]Ethyl]-1H-Imidazole
• 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-
• Lomexin
• Fenticonazole
• 1-[2,4-Dichloro-β-[[4-(phenylthio)benzyl]oxy]phenethyl]-1H-imidazole
• 1-[β-[[4-(Phenylthio)benzyl]oxy]-2,4-dichlorophenethyl]-1H-imidazole
• FENTICONAZOLE IMPURITY D(RS)-1-[2-(2,4-DICHLOROPHENYL)-2-HYDROXYETHYL]-3-[4-(PHENYLSUPHANYL)BENZYL]IMIDAZOLIUM NITRATE EPF(CRM STANDARD)

Fenticonazole Nitrate

CAS: 72479-26-6, 73151-29-8

Formula: C₂₄H₂₀Cl₂N₂OS·HNO₃

Purity: >97.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 518.41

Ref: 3B-F1008

Fenticonazole

CAS: 72479-26-6

Fenticonazole is an imidazole derivative with antibacterial and antifungal effects. fenticonazole has potential for mixed vaginitis studies.

Formula: C₂₄H₂₀Cl₂N₂OS

Color and Shape: Solid

Molecular weight: 455.4

Ref: TM-T62817

Fenticonazole 13C6, d2

Controlled Product

CAS: 72479-26-6

Formula: C₆C₁₈D₂H₁₈Cl₂N₂OS

Color and Shape: Neat

Molecular weight: 463.368

Ref: TR-F279157

Fenticonazole Nitrate-d9

Controlled Product

CAS: 72479-26-6

Formula: C₂₄H₁₁Cl₂D₉N₂OS·HNO₃

Color and Shape: Neat

Molecular weight: 455.399

Ref: TR-F279252

Fenticonazole

CAS: 72479-26-6

Formula: C₂₄H₂₀Cl₂N₂OS

Molecular weight: 455.4

Ref: ST-EA-CP-F30006