CAS 72496-59-4

Queuine

Description:

Queuine is a naturally occurring nucleobase that is classified as a modified form of guanine. It is primarily found in the tRNA of various organisms, where it plays a crucial role in the proper functioning of protein synthesis. Queuine is notable for its unique structure, which includes a 2-amino-6-oxopurine ring, contributing to its biological activity. It is involved in the modification of tRNA, specifically in the wobble position, which enhances the accuracy and efficiency of translation during protein synthesis. Queuine is synthesized in the body from dietary sources and is essential for cellular processes. Its presence is linked to various physiological functions, including cellular growth and differentiation. The compound has garnered interest in research due to its potential implications in health and disease, particularly in relation to cancer and metabolic disorders. Overall, queuine exemplifies the intricate relationship between nucleobases and cellular function, highlighting the importance of post-transcriptional modifications in gene expression.

Formula: C₁₂H₁₅N₅O₃

InChI: InChI=1S/C12H15N5O3/c13-12-16-10-8(11(20)17-12)5(4-15-10)3-14-6-1-2-7(18)9(6)19/h1-2,4,6-7,9,14,18-19H,3H2,(H4,13,15,16,17,20)/t6-,7-,9+/m0/s1

InChI key: InChIKey=WYROLENTHWJFLR-ACLDMZEESA-N

SMILES: C(N[C@@H]1[C@@H](O)[C@@H](O)C=C1)C=2C3=C(NC2)NC(N)=NC3=O

Synonyms:

• 2-amino-5-((((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-4H-pyrrolo(2,3-d)pyrimidin-4-one
• 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-, [1S-(1α,4β,5β)]-
• 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-
• Queuine

Queuine

CAS: 72496-59-4

Queuine is the base for nucleoside Q.

Formula: C₁₂H₁₅N₅O₃

Color and Shape: Solid

Molecular weight: 277.284

Ref: TM-T34221

Queuine

CAS: 72496-59-4

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Formula: C₁₂H₁₅N₅O₃

Purity: Min. 95%

Molecular weight: 277.28 g/mol

Ref: 3D-FQ183375