CAS 7250-43-3

N,N′-1,2-Ethanediylbis[2-iodoacetamide]

Description:

N,N′-1,2-Ethanediylbis[2-iodoacetamide], with the CAS number 7250-43-3, is a chemical compound characterized by its structure, which includes two iodoacetamide groups linked by an ethanediyl (ethylene) bridge. This compound typically appears as a solid at room temperature and is soluble in polar organic solvents. The presence of iodine atoms in its structure suggests that it may exhibit reactivity typical of halogenated compounds, potentially participating in nucleophilic substitution reactions. The amide functional groups contribute to its ability to form hydrogen bonds, which can influence its solubility and interaction with biological molecules. This compound may be of interest in various fields, including medicinal chemistry and biochemistry, due to its potential applications in drug design or as a biochemical probe. However, safety precautions should be taken when handling it, as compounds containing iodine can be hazardous. Overall, N,N′-1,2-Ethanediylbis[2-iodoacetamide] is a notable example of a halogenated amide with specific chemical properties that may be leveraged in research and development.

Formula: C₆H₁₀I₂N₂O₂

InChI: InChI=1/C6H10I2N2O2/c7-3-5(11)9-1-2-10-6(12)4-8/h1-4H2,(H,9,11)(H,10,12)

InChI key: InChIKey=RLFPCLMBTQOMLI-UHFFFAOYSA-N

SMILES: N(CCNC(CI)=O)C(CI)=O

Synonyms:

• 2-Iodo-N-[2-[(2-iodoacetyl)amino]ethyl]acetamide
• Acetamide, N,N′-ethylenebis[2-iodo-
• N,N′-1,2-Ethanediylbis[2-iodoacetamide]
• N,N′-Ethylenebis(iodoacetamide)
• NSC 30028
• acetamide, N,N'-1,2-ethanediylbis[2-iodo-
• N,N'-Ethane-1,2-diylbis(2-iodoacetamide)
• Nsc30028
• Ethylenediamine bis(iodoacetamide)
• S-25
• S 35
• Acetamide, N,N'-ethylenebis[iodo-
• Wln: I1vm2mv1i

N,N-Ethylenebis(iodoacetamide)

CAS: 7250-43-3

Formula: C₆H₁₀I₂N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 395.9647

Ref: IN-DA005GXC

N,N'-(Ethane-1,2-diyl)bis(2-iodoacetamide)

CAS: 7250-43-3

N,N'-(Ethane-1,2-diyl)bis(2-iodoacetamide)

Purity: 95%

Molecular weight: 395.97g/mol

Ref: 54-OR1071101

N,N’-Ethylenebis(iodoacetamide)

Controlled Product

CAS: 7250-43-3

Stability Sensitive to Light; Sensitive to Temperature, Unstable in DMSO
Applications Used as a probe for the conformational state of the tubulin molecule. It reacts specifically with the sulfhydryl groups in tubulin.
References Luduena, R.F., et al.: Biochemistry, 20, 4437 (1981), Sullivan, K.F.: Ann. Rev. Cell Biology, 4, 687 (1988), Sharma, J., et al.: Journal of Protein Chemistry, 13, 2, 165 (1994)

Formula: C₆H₁₀I₂N₂O₂

Color and Shape: Neat

Molecular weight: 395.96

Ref: TR-E917500

N,N'-Ethylenebis(iodoacetamide)

CAS: 7250-43-3

N,N'-Ethylenebis(iodoacetamide) is a molecule that binds to peptides and is used in cancer research. It has been shown to inhibit the growth of leukemia cells by inhibiting the synthesis of DNA. N,N'-Ethylenebis(iodoacetamide) has been shown to be an active analog for artemisinin, a drug used for malaria prophylaxis, and podophyllotoxin, a natural product used for the treatment of cancer. The molecule also inhibits cancer cell proliferation through its effects on protein synthesis.

Formula: C₆H₁₀I₂N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 395.96 g/mol

Ref: 3D-FE23141