CAS 72558-82-8

Ceftazidime

Description:

Ceftazidime is a third-generation cephalosporin antibiotic, primarily used to treat infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa. It is characterized by its broad-spectrum activity, making it effective against a variety of pathogens. The chemical structure of ceftazidime includes a beta-lactam ring, which is essential for its antibacterial activity, and a side chain that enhances its stability against certain beta-lactamases. Ceftazidime is typically administered via injection and is known for its relatively low toxicity profile. It is often used in hospital settings for serious infections, including pneumonia, urinary tract infections, and sepsis. The drug is generally well-tolerated, although potential side effects can include allergic reactions, gastrointestinal disturbances, and alterations in blood clotting. Its pharmacokinetics involve renal excretion, necessitating dosage adjustments in patients with impaired kidney function. Overall, ceftazidime remains a critical option in the antibiotic arsenal, particularly for treating resistant bacterial infections.

Formula: C₂₂H₂₂N₆O₇S₂

InChI: InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/t14-,18-/m1/s1

InChI key: InChIKey=ORFOPKXBNMVMKC-DWVKKRMSSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]=4C=CC=CC4)[H]

Synonyms:

• (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
• (6R,7R)-7-[(3Z)-3-(2-aminothiazol-4-yl)-3-(2-hydroxy-1,1-dimethyl-2-oxo-ethoxy)imino-2-oxo-propyl]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-[(Z)-2-(Aminothiazol-4-yl)-2-(2-carboxypropoxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate
• 1-(((6R,7R)-7-(((2Z)-(2-Amino-4-Thiazolyl)((1-Carboxy-1-Methylethoxy)Imino) Acetyl) Amino)-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo(4.2.0) Oct-2-En-3-Yl)Methyl)Pyridinum Hydroxide Inner Salt
• Biotum
• Cefazid
• Ceftacidin
• Ceftazidim
• Ceftazidima
• Ceftazidime anhydrous
• Ceftazidine
• Fortam
• Fortaz
• Fortum
• Gr 20263
• Modacin
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, [6R-[6α,7β(Z)]]-
• Solvetan
• Tazicef
• Tazid
• Tazidime
• Tizime
• Zidim
• Ceftazidime
• pyridinium,1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acety
• Kefadim
• Kefamin
• (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-2-[(Z)-1-carboxy-1-methylethoxyimino]acetylamino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• Stareef
• Tazicef：CAZ
• Panzid
• (6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• innersalt,(6r-(6-alpha,7-beta-(z)))-droxid
• gr20263
• C06889
• 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium Inner Salt
• Glazidim
• Ceftazidime/Sodium Carbonate
• CeftazidiMe with SodiuM Carbonate
• CeftazidiMe (C22H22N6O7S2 · xH2O)
• hy
• 72558-82-8
• Ceftim，Fortam
• thermogra
• CEFTAZIDIME HYDRATE
• [(6R-[6α，7β(Z)]]-1-[[7-[[(2-Amino-4-thiazolyl)[(1-earboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabieyelo[4.2.0]oct-2-en-3-y1]methyl]pyridinium inner salt
• sn401
• Ceptaz
• Ceftazidime (contains ca. 10% Na2CO3)
• caz

Ceftazidime (contains ca. 10% Na2CO3)

CAS: 72558-82-8

Formula: C₂₂H₂₂N₆O₇S₂

Purity: min. 98.0 area%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 546.57

Ref: 3B-C2225

Ceftazidime

CAS: 72558-82-8

Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity.

Formula: C₂₂H₂₂N₆O₇S₂

Purity: 99.1% - 99.85%

Color and Shape: Solid

Molecular weight: 546.58

Ref: TM-T1305

Ceftazidime

CAS: 72558-82-8

Formula: C₂₂H₂₂N₆O₇S₂

Molecular weight: 546.57

Ref: 4Z-C-10508

Ceftazidime

CAS: 72558-82-8

Ceftazidime

Purity: ≥98%

Molecular weight: 546.58g/mol

Ref: 54-BUP18065

Ceftazidime-d5

CAS: 72558-82-8

Formula: C₂₂H₁₇D₅N₆O₇S₂

Molecular weight: 551.60

Ref: 4Z-C-10511

Ceftazidime, Antibiotic for Culture Media Use Only

CAS: 72558-82-8

Ceftazidime is a fine chemical that can be used as a versatile building block for complex compounds. It is a useful reagent and research chemical. Ceftazidime is an important intermediate in the synthesis of other compounds and has been used as a reaction component to produce useful scaffolds. Ceftazidime has CAS No. 72558-82-8, making it a speciality chemical with high quality.

Formula: C₂₂H₂₂N₆O₇S₂

Purity: Min. 95.0 Area-%

Molecular weight: 546.57 g/mol

Ref: 3D-C-2510

Ceftazidime - Bio-X ™

CAS: 72558-82-8

Ceftazidime is a broad-spectrum beta-lactam antibiotic that inhibits bacterial growth by inhibiting penicillin-binding proteins (PBPs). It is used to treat many bacteria infections including pneumonia and septicaemia. It has shown to be effective against some treatment-resistant bacteria such as Pseudomonas aeruginosa.

Formula: C₂₂H₂₂N₆O₇S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 546.58 g/mol

Ref: 3D-BC300021

Ceftazidime

CAS: 72558-82-8

Ceftazidime is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like pneumonia, meningitis, and sepsis.

Formula: C₂₂H₂₂N₆O₇S₂

Purity: Min. 95.0 Area-%

Color and Shape: Powder

Molecular weight: 546.58 g/mol

Ref: 3D-FA153265