CAS: 72559-06-9 - Rifabutin

Formula: C₄₆H₆₂N₄O₁₁

InChI: InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14+/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1

InChI key: InChIKey=ATEBXHFBFRCZMA-NYGPAKPVSA-N

SMILES: O=C(OC1C(C)C(OC)C=COC2(OC=3C(C2=O)=C4C5=NC6(NC5=C(NC(=O)C(=CC=CC(C)C(O)C(C)C(O)C1C)C)C(=O)C4=C(O)C3C)CCN(CC6)CC(C)C)C)C

Synonyms:

• Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2′,3′:7,8]naphth[1,2-d]imidazole-2,4′-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1′-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-
• (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-16-(Acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1′-(2-methylpropyl)spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2′,3′:7,8]naphth[1,2-d]imidazole-2,4′-piperidine]-5,10,26(3H,9H)-trione
• Antibiotic LM 427
• Rifamycin XIV, 1′,4-didehydro-1-deoxy-1,4-dihydro-5′-(2-methylpropyl)-1-oxo-
• Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2′,3′:7,8]naphth[1,2-d]imidazole-2,4′-piperidine], rifamycin XIV deriv.

Rifabutin CRS

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Color and Shape: Amorphous. Reddish-Violet. Powder.
• Molecular weight: 847.0047

Rifabutin

CAS: 72559-06-9

Antibiotics nesoi

• Formula: C₄₆H₆₂N₄O₁₁
• Color and Shape: Dark Violet Powder
• Molecular weight: 846.44151

Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione,16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-,[9S-(9R*,12E,14R*,15S*,16R*,17S*,18S*,19S*,20R*,21R*,22E,24Z)]-

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 847.0047

Rifabutin

CAS: 72559-06-9

Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.

• Formula: C₄₆H₆₂N₄O₁₁
• Purity: 99.27% - 99.8%
• Color and Shape: Red-Violet Crystalline Powder
• Molecular weight: 847

Rifabutin

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Molecular weight: 847.02

Rifabutin

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Purity: 95.0 - 102.0 % (anhydrous basis)
• Color and Shape: Red to purple powder
• Molecular weight: 847.00

Rifabutin-d7

CAS: 72559-06-9

• Formula: C₄₆H₅₅D₇N₄O₁₁
• Color and Shape: Red Solid
• Molecular weight: 854.06

Rifabutin

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Purity: >98.0%(HPLC)
• Color and Shape: Red to Dark red to Dark purple powder to crystal
• Molecular weight: 847.02

Rifabutin

CAS: 72559-06-9

• Formula: C₄₆H₆₂N₄O₁₁
• Color and Shape: Neat
• Molecular weight: 847.00

Rifabutin

CAS: 72559-06-9

Inhibitor of bacterial DNA-dependent RNA polymerase

• Formula: C₄₆H₆₂N₄O₁₁
• Purity: Min. 97.5 Area-%
• Color and Shape: Powder
• Molecular weight: 847 g/mol