Intetumumab, identified by the CAS number 725735-28-4, is a monoclonal antibody that primarily targets the immune checkpoint protein known as CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). This protein plays a crucial role in downregulating immune responses, and by inhibiting its function, Intetumumab aims to enhance the immune system's ability to recognize and attack cancer cells. The substance is part of a broader class of immunotherapeutic agents that are being explored for their potential in treating various malignancies, particularly in oncology. Intetumumab is characterized by its specificity for CTLA-4, which is expressed on activated T cells, and its mechanism of action involves blocking the interaction between CTLA-4 and its ligands, thereby promoting T cell activation and proliferation. As a therapeutic agent, it is typically administered via injection and is subject to rigorous clinical evaluation to assess its efficacy and safety profile in cancer treatment.

Intetumumab

725735-28-4: Intetumumab, identified by the CAS number 725735-28-4, is a monoclonal antibody that primarily targets the immune checkpoint protein known as CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). This protein plays a crucial role in downregulating immune responses, and by inhibiting its function, Intetumumab aims to enhance the immune system's ability to recognize and attack cancer cells. The substance is part of a broader class of immunotherapeutic agents that are being explored for their potential in treating various malignancies, particularly in oncology. Intetumumab is characterized by its specificity for CTLA-4, which is expressed on activated T cells, and its mechanism of action involves blocking the interaction between CTLA-4 and its ligands, thereby promoting T cell activation and proliferation. As a therapeutic agent, it is typically administered via injection and is subject to rigorous clinical evaluation to assess its efficacy and safety profile in cancer treatment.

Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.

<p>Anti-EGFR human recombinant monoclonal antibody.</p>

CAS 725735-28-4

Intetumumab

Intetumumab

Ref: TM-T76812

Intetumumab

Ref: 3D-CLA1240