CAS 72578-71-3

3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

Description:

3-(2-Chloroacetyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide, with CAS number 72578-71-3, is a chemical compound that belongs to the class of oxazaphosphorines, which are characterized by a phosphorus atom bonded to an oxygen atom and incorporated into a cyclic structure. This compound features a tetrahydro-1,3,2-oxazaphosphorine ring, which contributes to its unique chemical properties. The presence of chloroacetyl and chloroethyl groups indicates that it may exhibit reactivity typical of alkylating agents, potentially allowing it to interact with nucleophiles in biological systems. Its structure suggests potential applications in medicinal chemistry, particularly in the development of anticancer agents, due to its ability to modify DNA. The compound is likely to be a solid at room temperature and may exhibit moderate solubility in organic solvents. Safety precautions should be taken when handling this substance, as it may pose health risks due to its reactive nature and potential toxicity.

Formula: C₇H₁₃Cl₂N₂O₃P

InChI: InChI=1/C14H28Cl2NO2P/c1-2-3-4-5-7-13(16)12-14-8-6-11-19-20(14,18)17-10-9-15/h13-14H,2-12H2,1H3,(H,17,18)

SMILES: CCCCCCC(CC1CCCOP1(=O)NCCCl)Cl

Synonyms:

• 2H-1,3,2-Oxazaphosphorin-2-amine,3-(chloroacetyl)-N-(2-chloroethyl)tetrahydro-2-oxide
• 3-(2-Chloroactyl)-2-[(2-chloroethyl)amino] tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
• IFOSFAMIDEACYLATE
• IfosfamideIntermediate
• ISOPHOSPHAMIDE INTERMEDIATE 72578-71-3
• 2H-1,3,2-Oxazaphosphorin-2-amine, 3-(chloroacetyl)-N-(2-chloroethyl)tetrahydro-, 2-oxide, (R)- (9CI)
• 3-(2-CHLOROACTYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE ,98%
• IfofaMide acylation objects
• 3-(2-CHLOROACETYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE
• Ifosfamide Compound III
• 2-chloro-1-[2-(2-chloroethylamino)-2-oxo-1,3,2$l^{5}-oxazaphosphorinan-3-yl]ethanone
• (R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone
• 3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin

2H-1,3,2-Oxazaphosphorin-2-amine,3-(chloroacetyl)-N-(2-chloroethyl)tetrahydro-, 2-oxide, (R)-

CAS: 72578-71-3

Formula: C₇H₁₃Cl₂N₂O₃P

Purity: 95%

Color and Shape: Solid

Molecular weight: 275.0695

Ref: IN-DA00ICA7

(R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone

CAS: 72578-71-3

(R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone

Purity: 95%

Molecular weight: 275.07g/mol

Ref: 54-OR1050737