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CAS 72600-65-8

:

2-fluoro-5-(trifluoromethyl)pyridin-3-amine

Description:
2-Fluoro-5-(trifluoromethyl)pyridin-3-amine is a chemical compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of a fluorine atom at the 2-position and a trifluoromethyl group at the 5-position significantly influences its chemical properties, including its reactivity and polarity. The amino group at the 3-position contributes to its basicity and potential for hydrogen bonding. This compound is typically used in pharmaceutical research and development due to its unique electronic properties and potential biological activity. Its trifluoromethyl group enhances lipophilicity, which can improve the compound's ability to penetrate biological membranes. Additionally, the presence of fluorine atoms often leads to increased metabolic stability. Overall, 2-fluoro-5-(trifluoromethyl)pyridin-3-amine is a valuable compound in medicinal chemistry, with applications in the synthesis of various biologically active molecules.
Formula:C6H4F4N2
InChI:InChI=1/C6H4F4N2/c7-5-4(11)1-3(2-12-5)6(8,9)10/h1-2H,11H2
SMILES:c1c(cnc(c1N)F)C(F)(F)F
Synonyms:
  • 2-Fluoro-5-(trifluoromethyl)-3-pyridinamine
  • 3-Pyridinamine, 2-Fluoro-5-(Trifluoromethyl)-
  • 72600-65-8
  • T6Nj Bf Cz Exfff
  • 2-Fluoro-5-(trifluoromethyl)pyridin-3-amine
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