CAS 72657-23-9

(R)-(-)-methyl B-hydroxyisobutyrate

Description:

(R)-(-)-Methyl β-hydroxyisobutyrate, with the CAS number 72657-23-9, is an organic compound characterized by its chiral structure, which includes a hydroxyl group and a methyl ester functional group. This compound is a derivative of isobutyric acid and is known for its role in various biochemical processes, particularly in the context of metabolic pathways. It is typically a colorless to pale yellow liquid with a pleasant odor, and it is soluble in water and organic solvents. The presence of the hydroxyl group contributes to its reactivity, allowing it to participate in various chemical reactions, including esterification and oxidation. As a chiral molecule, it exists in two enantiomeric forms, with the (R)-(-) configuration being of particular interest in pharmaceutical applications due to its potential biological activity. This compound is often used in research and development, particularly in the synthesis of other chiral compounds and in studies related to metabolic regulation and energy production.

Formula: C₅H₁₀O₃

InChI: InChI=1/C5H10O3/c1-4(3-6)5(7)8-2/h4,6H,3H2,1-2H3/t4-/m0/s1

SMILES: C[C@@H](CO)C(=O)OC

Synonyms:

• ()-Methyl D-beta-hydroxyisobutyrate
• Methyl (R)-()-3-hydroxy-2-methylpropionate
• (R)-(-)-3-hydroxy-2-methylpropionic*acid methyl E
• (R)-(-)-3-Hydroxyisobutyric acid methyl ester
• methyl (2R)-3-hydroxy-2-methyl-propanoate
• methyl (2S)-3-hydroxy-2-methylpropanoate

Methyl (R)-(-)-3-Hydroxyisobutyrate

CAS: 72657-23-9

Formula: C₅H₁₀O₃

Purity: >99.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 118.13

Ref: 3B-H0703

Methyl (R)-(-)-3-hydroxy-2-methylpropionate

CAS: 72657-23-9

Formula: C₅H₁₀O₃

Purity: 96%

Color and Shape: Liquid

Molecular weight: 118.1311

Ref: IN-DA003553

(R)-(-)-3-Hydroxy-2-methylpropionic acid methyl ester

CAS: 72657-23-9

(R)-(-)-3-Hydroxy-2-methylpropionic acid methyl ester

Formula: C₅H₁₀O₃

Purity: 96%

Color and Shape: clear. colourless liquid

Molecular weight: 118.13g/mol

Ref: 54-OR919434

(R)-3-Hydroxyisobutyric Acid Methyl Ester

Controlled Product

CAS: 72657-23-9

Applications Chiral derivative of 3-Hydroxyisobutyrate.
References Waldmann, H., et al.: Bioorg. Med. Chem., 2, 477 (1994), Vonstein, V., et al.: J. Bacteriol., 177, 4540 (1995),

Formula: C₅H₁₀O₃

Color and Shape: Neat

Molecular weight: 118.13

Ref: TR-H943558

(R)-Methyl 3-hydroxy-2-methylpropanoate

CAS: 72657-23-9

Formula: C₅H₁₀O₃

Purity: 96%

Color and Shape: Liquid, Clear

Molecular weight: 118.132

Ref: 10-F208677

(R)-3-Hydroxyisobutyric acid methyl ester

CAS: 72657-23-9

(R)-3-Hydroxyisobutyric acid methyl ester is a retronecine analogue that can be synthesized by hydrozirconation of an (R)-3-hydroxyisobutyryl chloride. The synthesis starts with the stereoselective formation of an acid lactone from a chiral intramolecular Diels-Alder reaction between a cyclic enol ether and a butenolide. This lactone is then converted to the desired product by lactonization followed by anion formation and mismatch elimination. The final step involves alkylation of the olefin with methyllithium, followed by acid hydrolysis to give the desired product.

Formula: C₅H₁₀O₃

Purity: Min. 95%

Molecular weight: 118.13 g/mol

Ref: 3D-FH24369