CAS 7266-47-9

adrenocorticotropic hormone fragment*1-17 human

Description:

Adrenocorticotropic hormone fragment 1-17 (ACTH 1-17) is a peptide derived from the larger adrenocorticotropic hormone, which is produced by the anterior pituitary gland. This fragment consists of the first 17 amino acids of the full-length ACTH and plays a role in stimulating the adrenal cortex to produce cortisol, a key hormone in stress response and metabolism. The CAS number 7266-47-9 identifies this specific peptide in chemical databases. ACTH 1-17 is characterized by its relatively small size, typically exhibiting a molecular weight that corresponds to its amino acid composition. It is soluble in water and exhibits biological activity, influencing various physiological processes, including immune response and energy metabolism. The fragment retains some of the biological functions of the full hormone, making it of interest in research related to endocrinology and potential therapeutic applications. Its stability, solubility, and bioactivity are critical for its use in scientific studies and potential clinical applications.

Formula: C₉₅H₁₄₅N₂₉O₂₃S

InChI: InChI=1/C89H133N27O22S/c1-49(2)73(85(135)102-45-70(120)104-58(20-9-11-32-90)76(126)109-63(87(137)138)23-14-35-99-89(95)96)115-84(134)69-24-15-36-116(69)86(136)62(21-10-12-33-91)105-71(121)44-101-75(125)66(40-52-42-100-57-19-8-7-18-55(52)57)112-77(127)59(22-13-34-98-88(93)94)106-80(130)65(38-50-16-5-4-6-17-50)111-82(132)67(41-53-43-97-48-103-53)113-78(128)60(29-30-72(122)123)107-79(129)61(31-37-139-3)108-83(133)68(47-118)114-81(131)64(110-74(124)56(92)46-117)39-51-25-27-54(119)28-26-51/h4-8,16-19,25-28,42-43,48-49,56,58-69,73,100,117-119H,9-15,20-24,29-41,44-47,90-92H2,1-3H3,(H,97,103)(H,101,125)(H,102,135)(H,104,120)(H,105,121)(H,106,130)(H,107,129)(H,108,133)(H,109,126)(H,110,124)(H,111,132)(H,112,127)(H,113,128)(H,114,131)(H,115,134)(H,122,123)(H,137,138)(H4,93,94,98)(H4,95,96,99)

SMILES: CC(C)C(C(=NCC(=NC(CCCCN)C(=NC(CCCNC(=N)N)C(=O)O)O)O)O)N=C(C1CCCN1C(=O)C(CCCCN)N=C(CN=C(C(Cc1c[nH]c2ccccc12)N=C(C(CCCNC(=N)N)N=C(C(Cc1ccccc1)N=C(C(Cc1cnc[nH]1)N=C(C(CCC(=O)O)N=C(C(CCSC)N=C(C(CO)N=C(C(Cc1ccc(cc1)O)N=C(C(CO)N)O)O)O)O)O)O)O)O)O)O)O

Synonyms:

• Acth (1-17)
• Synchrodyn
• alpha1-17-Corticotropin
• H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-OH
• Adrenocorticotropic hormone fragment 1-17 human (ACTH)
• SYSMEHFRWGKPVGKKR
• -Corticotropin
• ADRENOCORTICOTROPIC HORMONE (1-17), HUMAN
• alpha
• SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG
• ADRENOCORTICOTROPIC HORMONE FRAGMENT 1-17
• adrenocorticotropic hormone fragment 1-17 human, rat
• -ACTH
• ACTH (1-17), HUMAN
• ADRENOCORTICOTROPIC HORMONE (1-27)
• 1-17
• ALPHA 1-17-CORTICOTROPIN
• ADRENOCORTICOTROPIC HORMONE HUMAN FRAGMENT 1-17

ACTH (1-17)

CAS: 7266-47-9

Used for calibration in mass spectrometry.

Formula: C₉₅H₁₄₅N₂₉O₂₃S

Purity: 97.9%

Color and Shape: White Powder

Molecular weight: 2093.44

Ref: 01-4014222

ACTH (1-17)

CAS: 7266-47-9

Formula: C₉₅H₁₄₇N₂₉O₂₂S

Purity: 97%

Molecular weight: 2079.4298

Ref: IN-DA00FAJ6

ACTH (1-17)

CAS: 7266-47-9

ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.

Formula: C₉₅H₁₄₅N₂₉O₂₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 2093.41

Ref: TM-TP1011