CAS 72667-55-1

5-[(Methylamino)methyl]uridine

Description:

5-[(Methylamino)methyl]uridine, with the CAS number 72667-55-1, is a modified nucleoside that features a uridine base with a methylamino group attached to the 5-position via a methylene bridge. This compound is characterized by its structural similarity to uridine, which is one of the four nucleosides that make up RNA. The presence of the methylamino group enhances its solubility and may influence its biological activity, potentially affecting interactions with nucleic acids and enzymes. As a nucleoside analog, it may be of interest in various biochemical and pharmaceutical applications, including studies on RNA metabolism and the development of antiviral agents. Its properties, such as stability, reactivity, and interaction with biological systems, can vary based on environmental conditions like pH and temperature. Overall, 5-[(Methylamino)methyl]uridine represents a significant compound in the field of nucleoside chemistry, with potential implications in molecular biology and medicinal chemistry.

Formula: C₁₁H₁₇N₃O₆

InChI: InChI=1S/C11H17N3O6/c1-12-2-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h3,6-8,10,12,15-17H,2,4H2,1H3,(H,13,18,19)/t6-,7-,8-,10-/m1/s1

InChI key: InChIKey=ZXQHKBUIXRFZBV-FDDDBJFASA-N

SMILES: O=C1N(C=C(CNC)C(=O)N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

Synonyms:

• 5-[(Methylamino)methyl]uridine
• Uridine, 5-[(methylamino)methyl]-

5-[(Methylamino)methyl]uridine

CAS: 72667-55-1

5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).

Formula: C₁₁H₁₇N₃O₆

Purity: Min. 95%

Molecular weight: 287.27 g/mol

Ref: 3D-NM159410