Suc-Ala-Ala-Pro-Ala-pNA, also known as Succinyl-Ala-Ala-Pro-Ala-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays to study proteolytic enzymes, particularly serine proteases. This compound features a sequence of amino acids, including alanine and proline, with a succinyl group at one end and a p-nitroanilide moiety at the other, which serves as a chromogenic indicator. Upon enzymatic cleavage by specific proteases, the p-nitroanilide is released, leading to a measurable color change that can be quantified spectrophotometrically. The characteristics of this substance include its solubility in aqueous solutions, stability under physiological conditions, and specificity towards certain enzymes, making it a valuable tool in enzyme kinetics and inhibition studies. Its use in research helps elucidate the mechanisms of enzyme action and the development of potential therapeutic agents targeting proteolytic pathways. As with all chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its components.

Suc-Ala-Ala-Pro-Ala-pNA

72682-69-0: Suc-Ala-Ala-Pro-Ala-pNA, also known as Succinyl-Ala-Ala-Pro-Ala-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays to study proteolytic enzymes, particularly serine proteases. This compound features a sequence of amino acids, including alanine and proline, with a succinyl group at one end and a p-nitroanilide moiety at the other, which serves as a chromogenic indicator. Upon enzymatic cleavage by specific proteases, the p-nitroanilide is released, leading to a measurable color change that can be quantified spectrophotometrically. The characteristics of this substance include its solubility in aqueous solutions, stability under physiological conditions, and specificity towards certain enzymes, making it a valuable tool in enzyme kinetics and inhibition studies. Its use in research helps elucidate the mechanisms of enzyme action and the development of potential therapeutic agents targeting proteolytic pathways. As with all chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its components.

Suc-AAPA-pNA, an excellent substrate for porcine pancreatic elastase. Substrate for α-lytic protease.

CAS 72682-69-0

Suc-Ala-Ala-Pro-Ala-pNA

Suc-Ala-Ala-Pro-Ala-pNA

Ref: 01-4015680