Suc-Ala-Ala-Pro-Ile-pNA, also known as Succinyl-Ala-Ala-Pro-Ile-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for studying proteolytic enzymes. This compound features a sequence of amino acids, including alanine, proline, and isoleucine, which are linked by peptide bonds, and is modified with a succinyl group at one end and a p-nitroanilide moiety at the other. The presence of the p-nitroanilide group allows for colorimetric detection upon cleavage by enzymes, making it a valuable tool for enzyme activity assays. The peptide's structure contributes to its specificity and reactivity, influencing how it interacts with various proteases. In terms of solubility, it is generally soluble in aqueous solutions, which is advantageous for laboratory applications. Overall, Suc-Ala-Ala-Pro-Ile-pNA serves as an important substrate in enzymology, providing insights into enzyme kinetics and mechanisms.

Suc-Ala-Ala-Pro-Ile-pNA

72682-77-0: Suc-Ala-Ala-Pro-Ile-pNA, also known as Succinyl-Ala-Ala-Pro-Ile-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for studying proteolytic enzymes. This compound features a sequence of amino acids, including alanine, proline, and isoleucine, which are linked by peptide bonds, and is modified with a succinyl group at one end and a p-nitroanilide moiety at the other. The presence of the p-nitroanilide group allows for colorimetric detection upon cleavage by enzymes, making it a valuable tool for enzyme activity assays. The peptide's structure contributes to its specificity and reactivity, influencing how it interacts with various proteases. In terms of solubility, it is generally soluble in aqueous solutions, which is advantageous for laboratory applications. Overall, Suc-Ala-Ala-Pro-Ile-pNA serves as an important substrate in enzymology, providing insights into enzyme kinetics and mechanisms.

<p>Suc-Ala-Ala-Pro-Ile-pNA is an enzyme that belongs to the family of zymogens. It is a tetrapeptide that is synthesized in the cytosol and transported into the lumen of the intestine, where it is cleaved by trypsin to form pepsin A. In humans, this enzyme has been localized to the duodenum and jejunum. Suc-Ala-Ala-Pro-Ile-pNA is activated by trypsin and cleaves proteins at their carboxyl side chains. It also binds to specific residues in proteins, including those with unpaired cysteine residues.</p>

CAS 72682-77-0

Suc-Ala-Ala-Pro-Ile-pNA

Suc-Ala-Ala-Pro-Ile-pNA

Ref: 3D-FS110783