CAS 72711-43-4

gamma-melanocyte stimulating hormone

Description:

Gamma-melanocyte stimulating hormone (γ-MSH) is a peptide hormone that plays a crucial role in various physiological processes, particularly in the regulation of skin pigmentation and appetite. It is derived from the pro-opiomelanocortin (POMC) precursor and is known for its ability to stimulate melanogenesis, the process by which melanin is produced in melanocytes. This hormone interacts with melanocortin receptors, particularly the MC1R, influencing pigmentation in response to environmental factors such as UV radiation. In addition to its role in skin color, γ-MSH has been implicated in the modulation of energy homeostasis and inflammatory responses. The CAS number 72711-43-4 identifies this specific peptide in chemical databases, facilitating its study and application in research and potential therapeutic contexts. As a peptide, γ-MSH is characterized by its relatively short chain of amino acids, which contributes to its biological activity and specificity in receptor interactions. Understanding its properties and mechanisms can provide insights into skin biology and metabolic regulation.

Formula: C₇₄H₉₉N₂₁O₁₆S

γ₂-MSH

CAS: 72711-43-4

γ₂-MSH has been located in the cryptic region of the ACTH/β-lipotropin precursor protein from the intermediate lobe of bovine pituitary.

Formula: C₇₄H₉₉N₂₁O₁₆S

Purity: 98.7%

Color and Shape: White Lyophilisate

Molecular weight: 1570.8

Ref: 01-4008709

Gamma2-MSH

CAS: 72711-43-4

Gamma-MSH is a peptide hormone that is usually produced by the cells of the anterior pituitary gland. It has been shown to be a low potency natriuretic and anti-inflammatory cytokine. It has been found to bind to the receptor on granulosa cells and stimulate protein synthesis. Gamma-MSH also stimulates cAMP levels in myotubes, which leads to increased energy metabolism. This hormone has been shown to have physiological effects in various tissues including the heart and kidneys. Gamma-MSH upregulates genes that are involved in muscle contraction, cardiac function, and electrolyte balance. It also binds to receptors on camp levels and causes an increase in blood pressure through vasoconstriction.

Formula: C₇₄H₉₉N₂₁O₁₆S

Purity: Min. 95%

Molecular weight: 1,570.78 g/mol

Ref: 3D-FM109262