CAS 72795-01-8

2-Butanol,1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-,hydrochloride, (2R,3R)-rel- (9CI)

Description:

2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, hydrochloride, (2R,3R)-rel- (9CI) is a chemical compound characterized by its complex structure, which includes a butanol backbone substituted with an indene-derived moiety and an isopropylamino group. This compound is typically a white to off-white solid in its hydrochloride salt form, indicating its ionic nature and potential solubility in water. The presence of the hydroxyl group suggests it may exhibit moderate polarity, influencing its solubility and reactivity. The stereochemistry indicated by the (2R,3R)- designation implies specific spatial arrangements of its substituents, which can significantly affect its biological activity and interactions. As a hydrochloride salt, it is likely to be more stable and easier to handle than its free base form. This compound may have applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that could interact with biological targets. However, specific biological activities and safety profiles would require further investigation.

Formula: C₁₇H₂₇NO₂・ClH

Synonyms:

• 2-Butanol,1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-,hydrochloride, (R*,R*)-
• Ici 111581
• ICI 118551 hydrochloride

ICI 118551 (hydrochloride)

CAS: 72795-01-8

Formula: C₁₇H₂₈ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 313.8627

Ref: IN-DA005P11

ICI 118,551 hydrochloride

CAS: 72795-01-8

ICI 118,551 hydrochloride

Purity: ≥98%

Molecular weight: 313.86g/mol

Ref: 54-BUP21657

ICI 118,551 hydrochloride

CAS: 72795-01-8

ICI 118,551 hydrochloride (ICI 118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist (Kis: 0.7, 49.5, and 611 nM for β2, β1, and β3

Formula: C₁₇H₂₈ClNO₂

Purity: 99.296% - 99.76%

Color and Shape: Solid

Molecular weight: 313.86

Ref: TM-T11607

ICI 118551 Hydrochloride

Controlled Product

CAS: 72795-01-8

Applications The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.
References Bilski, A., et al.: J. Cardiovasc. Pharmacol., 5, 430 (1983), Furse, K., et al.: J. Med. Chem., 46, 4450 (2003), Cherezov, V., et al.: Science, 318, 1258 (2007),

Formula: C₁₇H₂₇NO₂·ClH

Color and Shape: Neat

Molecular weight: 313.86

Ref: TR-I163850

ICI 118551 hydrochloride

CAS: 72795-01-8

Antagonist of β2-adrenoceptor

Formula: C₁₇H₂₇NO₂•HCl

Purity: Min. 95%

Molecular weight: 313.86 g/mol

Ref: 3D-FI166401