CAS 72807-92-2
:Deoxydihydroartemisinin (α,β Mixture)
Description:
Deoxydihydroartemisinin (α,β Mixture), with the CAS number 72807-92-2, is a semi-synthetic derivative of artemisinin, which is derived from the sweet wormwood plant, Artemisia annua. This compound exhibits antimalarial properties and is primarily used in the treatment of malaria, particularly in cases resistant to conventional treatments. The mixture consists of two stereoisomers, α and β, which contribute to its pharmacological activity. Deoxydihydroartemisinin is characterized by its ability to generate reactive oxygen species upon activation, leading to the destruction of malaria parasites. It is typically administered in oral formulations and is known for its relatively low toxicity compared to other antimalarial agents. The compound is also being studied for potential applications in treating other diseases, including certain cancers, due to its cytotoxic effects on various cell lines. Its stability, solubility, and bioavailability are important factors influencing its efficacy and therapeutic use.
Formula:C15H24O4
Synonyms:- Deoxydihydroartemisinin (α,β Mixture)
- 10aH-9,10b-Epoxypyrano[4,3,2-jk][2]benzoxepin-2-ol, decahydro-3,6,9-trimethyl-, (3R,3aS,6R,6aS,9S,10aR,10bR)-
- Dihydroartemisinin Impurity 1
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 4 products.
Deoxy-Dihydroartemisinin
CAS:Formula:C15H24O4Color and Shape:White To Off-White SolidMolecular weight:268.35Deoxydihydroartemisinin (a,b Mixture)
CAS:Controlled ProductStability Hygroscopic
Applications Deoxydihydroartemisinin is used in biological studies antimalarial and possible antitumor effects via oxidative stress, modulated by hypoxia, in microendothelial cells.
References D’alessandro, S., et al.: Biochem. Pharm., 82, 476 (2011);Formula:C15H24O4Color and Shape:NeatMolecular weight:268.35Deoxydihydroartemisinin-d3
CAS:Controlled ProductFormula:C15D3H21O4Color and Shape:NeatMolecular weight:271.367
