CAS 72822-13-0

Dapiprazole hydrochloride

Description:

Dapiprazole hydrochloride is a pharmacological agent primarily used as a mydriatic reversal agent, particularly in ophthalmology to counteract the effects of pupil dilation induced by certain medications. It is classified as an alpha-adrenergic antagonist, which works by blocking alpha-1 adrenergic receptors, leading to the constriction of the pupil (miosis) and facilitating the return of normal vision after diagnostic procedures. The substance is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a pH range that is compatible with ocular formulations. Dapiprazole hydrochloride is administered topically as eye drops, and its effects are generally rapid, with a duration that allows for effective reversal of mydriasis. Safety and efficacy profiles have been established through clinical studies, although potential side effects may include local irritation or allergic reactions. As with any pharmaceutical, it is essential to follow appropriate dosing guidelines and consider contraindications when prescribing or using this compound.

Formula: C₁₉H₂₇N₅·ClH

InChI: InChI=1S/C19H27N5.ClH/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19;/h2-3,6-7H,4-5,8-15H2,1H3;1H

InChI key: InChIKey=ZIODNPFQZIHCOE-UHFFFAOYSA-N

SMILES: C(CN1CCN(CC1)C2=C(C)C=CC=C2)C=3N4C(=NN3)CCCC4.Cl

Synonyms:

• 1,2,4-Triazolo(4,3-a)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-, monohydrochloride
• 1,2,4-Triazolo[4,3-a]pyridine, 5,6,7,8-tetrahydro-3-[2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]-, hydrochloride (1:1)
• 5,6,7,8-Tetrahydro-3-(2-(4-o-tolyl-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine monohydrochloride
• Af 2139
• Dapiprazole HCl
• Dapiprazole monohydrochloride
• Glamidolo
• Rev-Eyes
• Reversil
• Unii-Ds9Ujn1I0X
• Dapiprazole hydrochloride

DapiprazoleHydrochloride

CAS: 72822-13-0

Formula: C₁₉H₂₈ClN₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 361.9121

Ref: IN-DA00FA4G

3-(2-(4-(O-Tolyl)Piperazin-1-Yl)Ethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyridine Hydrochloride

CAS: 72822-13-0

3-(2-(4-(O-Tolyl)Piperazin-1-Yl)Ethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyridine Hydrochloride

Purity: 99%

Molecular weight: 361.91g/mol

Ref: 54-OR1026170

Dapiprazole Hydrochloride

CAS: 72822-13-0

Dapiprazole Hydrochloride

Purity: ≥98%

Molecular weight: 361.92g/mol

Ref: 54-BUP13759

Dapiprazole Hydrochloride

CAS: 72822-13-0

Dapiprazole Hydrochloride (Glamidolo Hydrochloride) is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors.

Formula: C₁₉H₂₈ClN₅

Purity: 99.75% - 99.93%

Color and Shape: Solid

Molecular weight: 361.92

Ref: TM-T3996

Dapiprazole Hydrochloride

CAS: 72822-13-0

Applications Dapiprazole is an alpha blocker. Dapiprazole is used in the reversal of diagnostic mydriasis.
References Hogan, T.S. et al.: J. Ocular Pharmacol. Therap., 13, 297 (1997);

Formula: C₁₉H₂₇N₅·ClH

Color and Shape: Neat

Molecular weight: 361.9121

Ref: TR-D185450