CAS 72830-39-8

Oxmetidine

Description:

Oxmetidine is a chemical compound classified as an H2 receptor antagonist, primarily used for its anti-ulcer properties. It functions by inhibiting the action of histamine at the H2 receptors in the stomach lining, thereby reducing gastric acid secretion. This mechanism makes it effective in treating conditions such as peptic ulcers and gastroesophageal reflux disease (GERD). Oxmetidine is characterized by its ability to provide symptomatic relief from acid-related disorders. The compound is typically administered orally and is known for its relatively favorable safety profile, although potential side effects may include gastrointestinal disturbances and central nervous system effects. Its pharmacokinetics involve absorption in the gastrointestinal tract, with metabolism occurring in the liver. As with other H2 antagonists, it is important to consider drug interactions and contraindications when prescribing Oxmetidine. Overall, its role in managing acid-related conditions highlights its significance in therapeutic applications within gastroenterology.

Formula: C₁₉H₂₁N₅O₃S

InChI: InChI=1S/C19H21N5O3S/c1-12-15(23-10-22-12)9-28-5-4-20-19-21-8-14(18(25)24-19)6-13-2-3-16-17(7-13)27-11-26-16/h2-3,7-8,10H,4-6,9,11H2,1H3,(H,22,23)(H2,20,21,24,25)

InChI key: InChIKey=YTBDPHYVGACIPC-UHFFFAOYSA-N

SMILES: C(C=1C=C2C(=CC1)OCO2)C=3C(=O)NC(NCCSCC=4NC=NC4C)=NC3

Synonyms:

• Oxmetidine
• 4(3H)-Pyrimidinone, 5-(1,3-benzodioxol-5-ylmethyl)-2-[[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]amino]-
• 5-(1,3-Benzodioxol-5-ylmethyl)-2-[[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]amino]-4(3H)-pyrimidinone
• 4(1H)-Pyrimidinone, 5-(1,3-benzodioxol-5-ylmethyl)-2-[[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]amino]-
• SKF 92994

Oxmetidine

CAS: 72830-39-8

Oxmetidine

Purity: ≥98%

Molecular weight: 399.47g/mol

Ref: 54-BUP08378

Oxmetidine

CAS: 72830-39-8

Oxmetidine (SKF 92994) is an H2R antagonist that inhibits transmembrane calcium flux in the cardiovascular system and is used in the study of duodenal ulcers.

Formula: C₁₉H₂₁N₅O₃S

Purity: 99.67%

Color and Shape: Solid

Molecular weight: 399.47

Ref: TM-T68122