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CAS 72850-64-7

:

Flurazole

Description:
Flurazole, with the CAS number 72850-64-7, is a chemical compound that belongs to the class of azole antifungals. It is primarily characterized by its ability to inhibit the synthesis of ergosterol, a key component of fungal cell membranes, thereby exhibiting antifungal activity. Flurazole is typically used in the treatment of various fungal infections, particularly those caused by dermatophytes and yeasts. The compound is known for its broad-spectrum efficacy and is often formulated in topical applications. In terms of physical properties, Flurazole is generally a white to off-white solid, with moderate solubility in organic solvents and limited solubility in water. Its stability and effectiveness can be influenced by factors such as pH and temperature. As with many antifungal agents, the potential for resistance development is a consideration in its clinical use. Safety profiles indicate that it may cause mild side effects, but it is generally well-tolerated when used as directed.
Formula:C12H7ClF3NO2S
InChI:InChI=1S/C12H7ClF3NO2S/c13-11-17-9(12(14,15)16)8(20-11)10(18)19-6-7-4-2-1-3-5-7/h1-5H,6H2
InChI key:InChIKey=MKQSWTQPLLCSOB-UHFFFAOYSA-N
SMILES:C(OCC1=CC=CC=C1)(=O)C2=C(C(F)(F)F)N=C(Cl)S2
Synonyms:
  • Flurazole
  • Brn 1019538
  • Benzyl 2-chloro-4-(trifluoromethyl)-5-thiazolecarboxylate
  • Phenylmethyl 2-chloro-4-(trifluoromethyl)-5-thiazolecarboxylate
  • Screen
  • 5-Thiazolecarboxylic acid, 2-chloro-4-(trifluoromethyl)-, phenylmethyl ester
  • Benzyl 2-Chloro-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate
  • Benzyl 2-chloro-4-trifluoromethyl-1,3-thiaxole-5-carboxlate
  • 2-Chloro-4-(trifluoromethyl)-5-thiazolecarboxylic acid phenylmethyl ester
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