CAS 7291-41-0

6-Dehydroestradiol

Description:

6-Dehydroestradiol is a synthetic derivative of estradiol, a primary female sex hormone. It is characterized by its structural modifications that include the absence of a hydrogen atom at the 6-position of the steroid nucleus, which influences its biological activity and potency. This compound is classified as a steroid and is part of the estrogen class of hormones, playing a role in various physiological processes, including the regulation of the menstrual cycle and reproductive system. 6-Dehydroestradiol exhibits estrogenic activity, which can be utilized in therapeutic applications, particularly in hormone replacement therapy and the treatment of certain hormone-sensitive conditions. The compound is typically administered in a controlled manner due to its potent effects and potential side effects. Its chemical properties include solubility in organic solvents and limited solubility in water, which is common for steroid compounds. As with many synthetic hormones, careful consideration of dosage and administration is essential to minimize adverse effects and maximize therapeutic benefits.

Formula: C₁₈H₂₂O₂

InChI: InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h2-5,10,14-17,19-20H,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key: InChIKey=VVLCELUSWGWMSW-ZBRFXRBCSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(C=C3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]

Synonyms:

• (17Beta)-Estra-1(10),2,4,6-Tetraene-3,17-Diol
• (17β)-Estra-1,3,5(10),6-tetraene-3,17-diol
• 6-Dehydroestradiol
• Estra-1(10),2,4,6-Tetraene-3,17-Diol, (17Beta)-
• Estra-1,3,5(10),6-tetraen-3,17beta-diol
• Estra-1,3,5(10),6-tetraene-3,17-diol, (17.beta.)-
• Estra-1,3,5(10),6-tetraene-3,17-diol, (17beta)-
• Estra-1,3,5(10),6-tetraene-3,17-diol, (17β)-
• Estra-1,3,5(10),6-tetraene-3,17β-diol
• Estra-1,3,5(10)-6-tetraen-3,17β-diol
• NSC 57430
• Δ^6,7-Estradiol

Estradiol Related Compound B (1,3,5(10),6-estratetraen-3,17β-diol)

CAS: 7291-41-0

Estrogens and progestins

Formula: C₁₈H₂₂O₂

Color and Shape: White Yellow Crystalline Powder

Molecular weight: 270.16198

Ref: 45-1250020

Estra-1,3,5(10),6-tetraene-3,17β-diol (6,7-Didehydroestradiol)

CAS: 7291-41-0

Color and Shape: Neat

Ref: 86-MM0300.09

Estradiol Related Compound B

CAS: 7291-41-0

Formula: C₁₈H₂₂O₂

Molecular weight: 270.37

Ref: 4Z-E-0946

6,7-Dehydro Estradiol

CAS: 7291-41-0

Formula: C₁₈H₂₂O₂

Color and Shape: White To Off-White

Molecular weight: 270.37

Ref: TR-D229620

Estra-1,3,5(10),6-tetraene-3,17-diol

Controlled Product

CAS: 7291-41-0

Estra-1,3,5(10),6-tetraene-3,17-diol is a sulfonated derivative of estradiol. It is used as a ligand in binding assays to measure the affinity of various compounds for estrogens. Estra-1,3,5(10),6-tetraene-3,17-diol binds with high affinity to 17β-estradiol and other estrogens at the estrogen receptor. The binding of estradiol and its derivatives to the receptor leads to a conformational change that causes dissociation of heat shock proteins from the receptor. This results in an increase in transcriptional activity of the receptor and increased synthesis of mRNA.

Formula: C₁₈H₂₂O₂

Purity: Min. 95%

Molecular weight: 270.37 g/mol

Ref: 3D-FE59521

Estradiol USP Related Compound B

CAS: 7291-41-0

Formula: C₁₈H₂₂O₂

Molecular weight: 270.4

Ref: ST-EA-CP-E3009