CAS 72956-09-3
:Carvedilol
Description:
Carvedilol is a non-selective beta-adrenergic antagonist and alpha-1 blocker, primarily used in the management of hypertension and heart failure. Its chemical formula is C24H26N2O4, and it features a complex structure that includes a phenolic moiety and a chiral center, which contributes to its pharmacological activity. Carvedilol exhibits antioxidant properties and has been shown to improve left ventricular function in patients with heart failure. It works by blocking the effects of adrenaline on the heart and blood vessels, leading to decreased heart rate and blood pressure. The substance is typically administered orally and is well-absorbed, with a bioavailability that can be influenced by food intake. Carvedilol is generally well-tolerated, but potential side effects may include dizziness, fatigue, and hypotension. Its therapeutic effects are attributed to its ability to reduce cardiac workload and improve hemodynamics, making it a valuable medication in cardiovascular therapy.
Formula:C24H26N2O4
InChI:InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
InChI key:InChIKey=OGHNVEJMJSYVRP-UHFFFAOYSA-N
SMILES:O(CC(CNCCOC1=C(OC)C=CC=C1)O)C2=C3C=4C(NC3=CC=C2)=CC=CC4
Synonyms:- (.+-.)-Carvedilol
- 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
- 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]propan-2-ol
- Artist
- Bm 14190
- Cadilan
- Carca
- Cardivas
- Carloc
- Carvas
- Carvediol
- Carvexal
- Carvil
- Coreg
- Coronis
- Dilatrend
- Dimitone
- Dq 2466
- Eucardic
- Korvasan
- Kredex
- Querto
- Skf 105517
- Talliton
- Carvedilo
- CarvedilolEp5
- caredilol
- CarvedilolEdmf/Gmp
- 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-
- 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol 2,3-dihydroxybutanedioate (salt)
- Carvediloledmf/Gmpep5
- CarvedilolC24H26N204
- 1-(9h-carbozol-4-yloxy)-3-[[2-(2-methoxy phenoxy)ethyl] amino]-2-propanol
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Found 18 products.
Carvedilol
CAS:Formula:C24H26N2O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:406.48Carvedilol
CAS:CarvedilolFormula:C24H26N2O4Purity:99.8%Color and Shape:WhiteMolecular weight:406.18926CARVEDILOL CRS
CAS:<p>CARVEDILOL CRS</p>Formula:C24H26N2O4Color and Shape:Added ModifiedMolecular weight:406.4742CARVEDILOL FOR SYSTEM SUITABILITY CRS
CAS:<p>CARVEDILOL FOR SYSTEM SUITABILITY CRS</p>Formula:C24H26N2O4Color and Shape:Added ModifiedMolecular weight:406.4742Carvedilol
CAS:Cardiovascular drugs, nesoiFormula:C24H26N2O4Color and Shape:White Off-White Crystalline PowderMolecular weight:406.18926Carvedilol
CAS:<p>Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.</p>Formula:C24H26N2O4Purity:99.73% - 99.97%Color and Shape:Colourless Crystalline PowderMolecular weight:406.47Carvedilol
CAS:Formula:C24H26N2O4Purity:≥ 98.0% (dried basis)Color and Shape:White or almost white crystalline powderMolecular weight:406.47Carvedilol
CAS:Controlled Product<p>Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);<br></p>Formula:C24H26N2O4Color and Shape:WhiteMolecular weight:406.47Carvedilol - Bio-X ™
CAS:Controlled Product<p>Carvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.</p>Formula:C24H26N2O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:406.47 g/molCarvedilol
CAS:Controlled Product<p>Carvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.</p>Formula:C24H26N2O4Purity:Min. 98.5 Area-%Color and Shape:White Off-White PowderMolecular weight:406.47 g/molCarvedilol-13C6
CAS:Controlled ProductFormula:C6C18H26N2O4Color and Shape:NeatMolecular weight:412.43Carvedilol-13C3
CAS:Controlled ProductFormula:C3C21H26N2O4Color and Shape:NeatMolecular weight:409.4521-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
CAS:Formula:C24H26N2O4Purity:98%Color and Shape:SolidMolecular weight:406.4742
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