CAS 72957-38-1

dynorphin A fragment 1-13

Description:

Dynorphin A fragment 1-13 is a peptide derived from the larger dynorphin A molecule, which is part of the endogenous opioid peptide family. This fragment consists of 13 amino acids and is known for its role in modulating pain, stress responses, and various neurophysiological processes. It primarily interacts with the kappa-opioid receptors in the central nervous system, contributing to its analgesic effects. The peptide exhibits characteristics typical of opioid peptides, including the ability to induce analgesia and influence mood and emotional responses. Its structure includes specific sequences that are crucial for receptor binding and activity. Additionally, dynorphin A fragment 1-13 may have implications in various neurological conditions and is of interest in research related to addiction, depression, and other mood disorders. As a synthetic or naturally occurring peptide, it can be studied for its pharmacological properties and potential therapeutic applications.

Formula: C₇₅H₁₂₆N₂₄O₁₅

InChI: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Synonyms:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: 91.6%

Color and Shape: White Powder

Molecular weight: 1603.98

Ref: 01-4004062

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: 98%

Molecular weight: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 1603.95

Ref: TM-TP1179

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Purity: 99%

Molecular weight: 1,603.95g/mol

Ref: 54-BISN0009

Dynorphin A (1-13)

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₇₅H₁₂₆N₂₄O₁₅

Molecular weight: 1,603.95 g/mol

Ref: 3D-PP50465

Dynorphin A (1-12), porcine

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₆₉H₁₁₄N₂₂O₁₄

Molecular weight: 1,475.82 g/mol

Ref: 3D-PP50361

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: Min. 95%

Molecular weight: 1,604 g/mol

Ref: 3D-PDY-4080-V

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Formula: C₇₅H₁₂₆N₂₄O₁₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13), Porcine

CAS: 72957-38-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Color and Shape: Lyophilized powder

Ref: 02-J64015