CAS 729589-58-6

N-(2-Furanylcarbonyl)-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucyl-L-ornithinamide

CAS: 729589-58-6

Formula: C₃₆H₆₃N₁₁O₈

Purity: 95%

Color and Shape: Solid

Molecular weight: 777.9543

Ref: IN-DA00F9ZO

2-Furoyl-LIGRLO-amide

CAS: 729589-58-6

2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.

Formula: C₃₆H₆₃N₁₁O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 777.95

Ref: TM-TP1478

2-Furoyl-LIGRLO-amide trifluoroacetate salt

CAS: 729589-58-6

Potent agonist of proteinase-activated receptor-2 (PAR2)

Formula: C₃₆H₆₃N₁₁O₈

Color and Shape: Powder

Molecular weight: 777.96 g/mol

Ref: 3D-FF109770

2-Furoyl-LIGRLO-amide acetate salt

CAS: 729589-58-6

2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2 is a synthetic peptide that binds to the 5HT3 receptor. It has been shown to have an effect on locomotor activity and growth factor secretion in wild type mice and cell culture, as well as binding to acetylcholine receptors in C57/BL6 mice. 2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn was synthesized by the reaction of furoic acid with L -alanine, L -glycine, L -arginine and L -ornithine. The product is a white powder.

Formula: C₃₆H₆₃N₁₁O₈

Purity: Min. 95%

Molecular weight: 777.96 g/mol

Ref: 3D-PAR-3663-PI

(2-Furoyl)-PAR-2 (2-6)-Orn amide (mouse, rat)

CAS: 729589-58-6

2-(2-Furoyl)-PAR-2 (2-6)-Orn amide (mouse, rat) is a potent and selective PAR-2 agonist. In cultured human PAR-2-expressing cells (2-Furoyl)-LIGRLO-amide was equally effective as SLIGRL-amide, in rat PAR-2-expressing cells it was 10 to 25 times more potent than SLIGRLamide in increasing intracellular calcium levels. In bioassays of tissue PAR-2 activity, measured as arterial vasodilation and hyperpolarization this agonist was 10 to 300 times more potent than SLIGRLamide.

Formula: C₃₆H₆₃N₁₁O₈

Purity: 98.0%

Color and Shape: Yellowish Lyophilisate

Molecular weight: 777.97

Ref: 01-4048620