CAS 73-05-2

Phentolamine hydrochloride

Description:

Phentolamine hydrochloride is a non-selective alpha-adrenergic antagonist primarily used in the treatment of hypertension and to manage pheochromocytoma, a tumor of the adrenal gland that secretes catecholamines. It is a white to off-white crystalline powder that is soluble in water and has a pH range of 4.5 to 6.5 in solution. The compound acts by blocking alpha-1 and alpha-2 adrenergic receptors, leading to vasodilation and a decrease in blood pressure. Its chemical formula is C17H20N2•HCl, and it has a molecular weight of approximately 288.82 g/mol. Phentolamine is often administered via injection and can also be used in dental procedures to reverse the effects of local anesthetics. Side effects may include tachycardia, hypotension, and gastrointestinal disturbances. Due to its pharmacological properties, it is important to monitor patients closely during treatment to manage potential adverse effects effectively.

Formula: C₁₇H₁₉N₃O·ClH

InChI: InChI=1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H

InChI key: InChIKey=TUEJFGFQYKDAPM-UHFFFAOYSA-N

SMILES: N(CC=1NCCN1)(C2=CC(O)=CC=C2)C3=CC=C(C)C=C3.Cl

Synonyms:

• Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, hydrochloride (1:1)
• Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, monohydrochloride
• Phenol, m-[N-(2-imidazolin-2-ylmethyl)-p-toluidino]-, monohydrochloride
• Phentolamine HCl
• Phentolamine chloride
• Regitine hydrochloride
• hydrogen chloride 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol (1:1:1)
• m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol hydrochloride
• DNP

Phentolamine Hydrochloride

CAS: 73-05-2

Color and Shape: Neat

Ref: 61-FOR3187.00

Phentolamine HCl

CAS: 73-05-2

Formula: C₁₇H₂₀ClN₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.8132

Ref: IN-DA00FARQ

Phentolamine hydrochloride

CAS: 73-05-2

Formula: C₁₇H₁₉N₃O·HCl

Purity: ≥ 98.0%

Color and Shape: White to beige or light-brown crystalline powder

Molecular weight: 317.81

Ref: 7W-GP4101

Phentolamine (hydrochloride)

CAS: 73-05-2

Phentolamine (hydrochloride)

Purity: ≥95%

Molecular weight: 317.82g/mol

Ref: 54-OR1007419

PHENTOLAMINE HYDROCHLORIDE

CAS: 73-05-2

Purity: 95%

Molecular weight: 317.820007324219

Ref: 10-F849455

Phentolamine Hydrochloride

CAS: 73-05-2

Formula: C₁₇H₁₉N₃O·ClH

Color and Shape: Neat

Molecular weight: 317.81

Ref: 86-MM3187.00

Phentolamine hydrochloride

CAS: 73-05-2

Phentolamine hydrochloride is a blocking agent of adrenergic α receptor that is orally active [1].

Formula: C₁₇H₂₀ClN₃O

Color and Shape: Solid

Molecular weight: 317.82

Ref: TM-T60834

Phentolamine Hydrochloride

Controlled Product

CAS: 73-05-2

Applications Phentolamine Hydrochloride ia an adrenergic blocking agent. An antihypertensive. Used for the treatment of pheochromocytoma.
References Meier, R., et al.: Proc. Soc. Exp. Biol. Med., 71, 70 (1949), Spergel, G., et al.: J. Am. Med. Assoc., 211, 266 (1970), Gould, L. and Reddy, C.V.R.: Am. Heart J., 92, 397 (1976)

Formula: C₁₇H₁₉N₃O·ClH

Color and Shape: Neat

Molecular weight: 317.81

Ref: TR-P302550

Phentolamine hydrochloride

CAS: 73-05-2

α-adrenoceptor antagonist

Formula: C₁₇H₂₀ClN₃O

Purity: Min. 95%

Molecular weight: 317.81 g/mol

Ref: 3D-FP26895