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CAS 73025-68-0

:

(R)-3-Amino-3-(4-hydroxyphenyl)propionic acid

Description:
(R)-3-Amino-3-(4-hydroxyphenyl)propionic acid, commonly known as L-DOPA, is an amino acid derivative characterized by its role as a precursor to neurotransmitters, particularly dopamine. This compound features a chiral center, which contributes to its specific biological activity, with the (R) configuration being the biologically active form. It possesses both an amino group and a carboxylic acid group, making it an α-amino acid. The presence of a 4-hydroxyphenyl group enhances its solubility and reactivity, allowing it to participate in various biochemical pathways. L-DOPA is primarily used in the treatment of Parkinson's disease and is known for its ability to cross the blood-brain barrier, where it is converted to dopamine. Its pharmacological properties include neuroprotective effects and the ability to alleviate motor symptoms associated with dopamine deficiency. Additionally, L-DOPA is subject to enzymatic conversion and can undergo oxidation, which is important for its therapeutic efficacy and metabolism. Overall, its unique structure and properties make it a significant compound in both biochemistry and medicine.
Formula:C9H11NO3
Synonyms:
  • R-3-Amino-3-(4-hydroxyphenyl)-propionic acid
  • (R)-4-Hydroxy-Beta-Phenylalanine
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