CAS 73027-02-8

(1S,3R)-5,12-dihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside hydrochloride (1:1)

Description:

The chemical substance known as "(1S,3R)-5,12-dihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside hydrochloride (1:1)" with CAS number 73027-02-8 is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as hydroxyl (-OH), methoxy (-OCH3), and amino (-NH2) groups. This compound features a tetracene backbone, which contributes to its unique chemical properties and potential biological activity. The presence of the trideoxy-hexopyranoside moiety suggests that it may exhibit glycosidic properties, potentially influencing its solubility and reactivity. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, enhancing its bioavailability. The stereochemistry indicated by the (1S,3R) configuration suggests specific spatial arrangements that could be crucial for its interaction with biological targets. Overall, this compound may have applications in medicinal chemistry, particularly in the development of therapeutic agents.

Formula: C₂₇H₃₀ClNO₁₀

InChI: InChI=1/C27H29NO10.ClH/c1-10-23(31)14(28)8-18(37-10)38-17-7-11(15(30)9-29)6-13-20(17)27(35)22-21(25(13)33)24(32)12-4-3-5-16(36-2)19(12)26(22)34;/h3-5,10-11,14,17-18,23,29,31,33,35H,6-9,28H2,1-2H3;1H/t10-,11+,14-,17-,18-,23+;/m0./s1

Synonyms:

• 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8R-trans)-

9-Deoxydoxorubicin Hydrochloride

Controlled Product

CAS: 73027-02-8

Applications 9-Deoxydoxorubicin is an anthracycline antibiotic used in the treatment off cancer cells.
References Cashman, D. et al.: J. Med. Chem., 47, 1360 (2004); Cashman, D. et al.: Nucl. Acids Res., 31, 4410 (2003);

Formula: C₂₇H₂₉NO₁₀·HCl

Color and Shape: Neat

Molecular weight: 563.98

Ref: TR-D232810