CAS 7306-68-5

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

Description:

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine, with the CAS number 7306-68-5, is a purine derivative characterized by the presence of a chlorine atom at the 6-position and a tetrahydro-2H-pyran-2-yl group at the 9-position of the purine ring. This compound exhibits properties typical of purines, including potential biological activity, as purines are fundamental components of nucleic acids and play crucial roles in cellular metabolism. The chlorine substituent can influence the compound's reactivity and solubility, while the tetrahydropyran moiety may enhance lipophilicity, potentially affecting its pharmacokinetic properties. The structural features suggest that it may interact with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, 6-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine represents a unique structure within the purine class, with potential applications in drug development and biochemistry.

Formula: C₁₀H₁₁ClN₄O

InChI: InChI=1/C10H11ClN4O/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-16-7/h5-7H,1-4H2

InChI key: InChIKey=QSTASPNCKDPSAH-UHFFFAOYSA-N

SMILES: ClC1=C2C(N(C=N2)C3CCCCO3)=NC=N1

Synonyms:

• 6-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
• 6-Chloro-9-(tetrahydropyran-2-yl)-9H-purine
• 6-Chloro-9-(tetrahydropyran-2-yl)purine
• 6-Chloropurine-THP
• 9-(Tetrahydropyran-2-yl)-6-chloropurine
• 9H-Purine, 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-
• 9H-Purine, 6-chloro-9-(tetrahydropyran-2-yl)-
• NSC 33187
• 6-chloro-9-(tetrahydro-2-pyranyl)purine
• 6-Chloro-9-(tetrahydro-2-pyranyl)-purine
• TIMTEC-BB SBB005344
• 6-Chloro-9-Thp-9H-purine

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

CAS: 7306-68-5

Formula: C₁₀H₁₁ClN₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.6735

Ref: IN-DA003N68

6-Chloro-9-(tetrahydro-2-pyranyl)purine

CAS: 7306-68-5

Intermediate and building block-electrophile, heterocyclic compound-purine

Formula: C₁₀H₁₁ClN₄O

Color and Shape: Solid

Molecular weight: 238.67

Ref: TM-TNU0669

6-Chloro-9-(tetrahydropyran-2-yl)purine

CAS: 7306-68-5

6-Chloro-9-(tetrahydropyran-2-yl)purine

Purity: 98%

Molecular weight: 238.67g/mol

Ref: 54-OR322354

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)purine

CAS: 7306-68-5

6-Chloro-9-(tetrahydro-2H-pyran-2-yl)purine is a nucleoside analog that is used to treat various types of cancer. It is a c–h bond regiospecific nucleophile that forms the 6-chloro 9-(tetrahydro-2H-pyran-2-yl)purine intermediate. The chloride ion acts as a nucleophile in the first step of this process, which results in the formation of an organocuprate and glyoxylate. 6CPP binds to DNA and inhibits RNA synthesis, leading to cell death by apoptosis or necrosis. This drug has been shown to be effective for treating human cell lines. 6CPP is also known for its antitumor effects, which may be due to its ability to inhibit phosphonates and cross-coupling reactions.

Formula: C₁₀H₁₁ClN₄O

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 238.67 g/mol

Ref: 3D-FC08313

6-Chloro-9-(tetrahydropyran-2-yl)-9H-purine

CAS: 7306-68-5

Formula: C₁₀H₁₁ClN₄O

Purity: 95%

Color and Shape: Solid

Molecular weight: 238.68

Ref: 10-F049307