CAS 73069-14-4

Atractylenolide II

Description:

Atractylenolide II is a bioactive compound primarily derived from the roots of the traditional Chinese medicinal herb Atractylodes macrocephala. It belongs to the class of sesquiterpenes and is known for its various pharmacological properties. This compound typically exhibits anti-inflammatory, antioxidant, and immunomodulatory effects, making it of interest in both traditional medicine and modern pharmacology. Atractylenolide II has been studied for its potential therapeutic applications, including its role in enhancing digestive health and its effects on the immune system. The substance is characterized by its relatively low solubility in water but is soluble in organic solvents, which is common for many terpenoids. Its molecular structure features a bicyclic framework, contributing to its biological activity. Research continues to explore its mechanisms of action and potential uses in treating various health conditions, highlighting its significance in both herbal medicine and pharmaceutical development.

Formula: C₁₅H₂₀O₂

InChI: InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h12-13H,1,4-8H2,2-3H3/t12-,13-,15+/m0/s1

InChI key: InChIKey=OQYBLUDOOFOBPO-KCQAQPDRSA-N

SMILES: C[C@]12[C@@](CC=3[C@](C1)(OC(=O)C3C)[H])(C(=C)CCC2)[H]

Synonyms:

• (4aS,8aR,9aS)-3,8a-Dimethyl-4-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
• (4aS,8aR,9aS)-3,8a-dimethyl-4-methylidene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one
• (4aS,8aR,9aS)-4a,5,6,7,8,8a,9,9a-Octahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
• 2-Atractylenolide
• Asterolide
• Eudesma-4(15),7(11)-dien-8α,12-olide
• Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-5-methylene-, (4aS,8aR,9aS)-
• Naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-5-methylene-, [4aS-(4aα,8aβ,9aβ)]-
• naphtho[2,3-b]furan-2(4H)-one, 4a,5,6,7,8,8a,9,9a-octahydro-3,8a-dimethyl-4-methylene-, (4aS,8aR,9aS)-
• Atractylenolide II

2-Atractylenolide

CAS: 73069-14-4

Formula: C₁₅H₂₀O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 232.3181

Ref: IN-DA00FAFQ

Atractylenolide II

CAS: 73069-14-4

Atractylenolide II

Purity: ≥98%

Molecular weight: 232.32g/mol

Ref: 54-BUP00083

Atractylenolide II

CAS: 73069-14-4

Formula: C₁₅H₂₀O₂

Molecular weight: 232.32

Ref: 7W-GY8300

Atractylenolide II

CAS: 73069-14-4

Atractylenolide II has antiinflammatory activity, it can inhibit platelets activities and thrombus formation. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation ,ERK and Akt inactivation, p53 dependent, it also has antimelanoma effect by inhibiting STAT3 signalling.

Formula: C₁₅H₂₀O₂

Purity: 95%~99%

Molecular weight: 232.323

Ref: BP-BP0215

Atractylenolide II

CAS: 73069-14-4

Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.

Formula: C₁₅H₂₀O₂

Purity: 99.89% - 99.93%

Color and Shape: Solid

Molecular weight: 232.32

Ref: TM-T5S0168

Atractylenolide ii

CAS: 73069-14-4

Lactone

Formula: C₁₅H₂₀O₂

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 232.32

Ref: 5G-82480

AtractylenolideII

CAS: 73069-14-4

Atractylenolide II is a sesquiterpenoid lactone, which is primarily isolated from the medicinal herb Atractylodes lancea. This compound is a naturally occurring secondary metabolite found in the root of the plant, a source well-regarded in traditional Chinese medicine. Atractylenolide II exerts its effects through various biological mechanisms, including modulation of the immune response, anti-inflammatory activity, and inhibition of certain signaling pathways that contribute to cellular proliferation and inflammation.

Formula: C₁₅H₂₀O₂

Purity: Min. 95%

Molecular weight: 232.32 g/mol

Ref: 3D-FA73866