CAS 731-98-6

5′-Deoxy-5′-fluoroadenosine

Description:

5′-Deoxy-5′-fluoroadenosine, with the CAS number 731-98-6, is a modified nucleoside that features a fluorine atom substituted at the 5′ position of the adenosine molecule. This substitution alters its biochemical properties, making it a valuable compound in biochemical research and potential therapeutic applications. The presence of the fluorine atom enhances the stability of the nucleoside against enzymatic degradation, which can be advantageous in drug design. It retains the purine base structure characteristic of adenosine, allowing it to participate in various biochemical pathways, including those related to nucleic acid metabolism. The compound is often studied for its potential role in antiviral and anticancer therapies, as modifications to nucleosides can influence their interaction with enzymes and receptors. Additionally, 5′-Deoxy-5′-fluoroadenosine can serve as a useful tool in the study of nucleoside transport and metabolism, providing insights into cellular processes and the development of nucleoside analogs.

Formula: C₁₀H₁₂FN₅O₃

InChI: InChI=1S/C10H12FN5O3/c11-1-4-6(17)7(18)10(19-4)16-3-15-5-8(12)13-2-14-9(5)16/h2-4,6-7,10,17-18H,1H2,(H2,12,13,14)/t4-,6-,7-,10-/m1/s1

InChI key: InChIKey=QPVLKMICBYRPSX-KQYNXXCUSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CF)[C@H]1O

Synonyms:

• 7: PN: WO2004078914 PAGE: 160 claimed sequence
• Adenosine, 5′-deoxy-5′-fluoro-
• 5′-Fluoro-5′-deoxyadenosine
• 5′-Deoxy-5′-fluoroadenosine

5′-Deoxy-5′-fluoroadenosine

CAS: 731-98-6

Formula: C₁₀H₁₂FN₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 269.2324

Ref: IN-DA01EF6G

5'-Fluoro-5'-deoxyadenosine

CAS: 731-98-6

5'-Fluoro-5'-deoxyadenosine

Purity: ≥95%

Molecular weight: 269.23g/mol

Ref: 54-BUP12641

5'-Fluoro-5'-deoxyadenosine

CAS: 731-98-6

5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) is utilized commonly as a tool for studying the Actinomycete bacterium Streptomyces cattleya.

Formula: C₁₀H₁₂FN₅O₃

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 269.23

Ref: TM-T60020

(2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(fluoromethyl)tetrahydrofuran-3,4-diol

CAS: 731-98-6

Purity: 98%

Molecular weight: 269.2359924

Ref: 10-F959503

5'-Fluoro-5'-deoxy-adenosine

CAS: 731-98-6

5'-Fluoro-5'-deoxy-adenosine (FDA) is a fluorinated adenosine derivative that has been shown to regulate glucose levels in plasma. It has been shown to increase the uptake of glucose in cells and improve insulin sensitivity, which may be due to its ability to increase the production of nitric oxide. FDA is also thought to act as an antioxidant and may be useful for treating autoimmune diseases such as insulin resistance and type II diabetes.

Formula: C₁₀H₁₂FN₅O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 269.23 g/mol

Ref: 3D-FP158773