CAS 73121-56-9

Enprostil

Description:

Enprostil is a synthetic compound classified as a prostaglandin analog, specifically designed to mimic the effects of natural prostaglandins in the body. It is primarily known for its role in gastrointestinal protection, particularly in the prevention of gastric ulcers and the promotion of mucosal healing. Enprostil functions by stimulating the secretion of mucus and bicarbonate in the stomach, enhancing the protective lining against acidic environments. Additionally, it has anti-inflammatory properties, making it useful in various therapeutic applications. The compound is typically administered orally and is characterized by its relatively low toxicity profile. Its chemical structure includes a carboxylic acid group, which is essential for its biological activity. Enprostil's pharmacokinetics involve rapid absorption and metabolism, leading to a relatively short half-life, which necessitates multiple dosing for sustained effects. Overall, Enprostil represents a significant advancement in gastroprotective therapies, offering a targeted approach to managing gastric health.

Formula: C₂₃H₂₈O₆

InChI: InChI=1S/C23H28O6/c1-28-23(27)12-8-3-2-7-11-19-20(22(26)15-21(19)25)14-13-17(24)16-29-18-9-5-4-6-10-18/h3-7,9-10,13-14,17,19-20,22,24,26H,8,11-12,15-16H2,1H3/b14-13+/t2?,17-,19-,20-,22-/m0/s1

InChI key: InChIKey=PTOJVMZPWPAXER-FPXSIRDUSA-N

SMILES: C(=C/[C@@H](COC1=CC=CC=C1)O)\[C@H]2[C@H](CC=C=CCCC(OC)=O)C(=O)C[C@@H]2O

Synonyms:

• 4,5-Heptadienoic acid, 7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)-, methyl ester
• 4,5-Heptadienoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-, methyl ester, rel-
• 4,5-Heptadienoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-butenyl]-5-oxocyclopentyl]-, methyl ester, rel-
• Camleed
• Enprostil [USAN:INN:BAN:JAN]
• Enprostilo
• Enprostilo [Spanish]
• Enprostilum
• Enprostilum [Latin]
• Fundyl
• Gardrin
• Gardrine
• Methyl 7-((1R*,2R*,3R*)-3-hydroxy-2-((E)-(3R*)-3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)-4,5-heptadienoate
• Rs 84-135
• Rs 84135
• Rs 84135-004
• Syngard
• methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl}hepta-4,5-dienoate
• methyl 7-{(1S,2S,3S)-3-hydroxy-2-[(1Z,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl}hepta-4,5-dienoate

Enprostil

CAS: 73121-56-9

Formula: C₂₃H₂₈O₆

Color and Shape: Liquid

Molecular weight: 400.4648

Ref: IN-DA00FB7W

Enprostil

CAS: 73121-56-9

Formula: C₂₃H₂₈O₆

Molecular weight: 400.46

Ref: 7W-GP4458

rac-Enprostil

Controlled Product

CAS: 73121-56-9

Stability Light Sensitive
Applications Enprostil is a synthetic analogue of prostaglandin E2 and was found to be effective in the treatment of patients with duodenal or gastric ulcers.
References Goa, K.L., et al.: Drugs., 34, 539 (1987); Higuchi, K., et al.: Inflammopharmacol., 15, 18 (2006); Murata, H., et al.: Hepato-Gastroenterol., 52, 1925 (2005);

Formula: C₂₃H₂₈O₆

Color and Shape: Neat

Molecular weight: 400.46

Ref: TR-E557700

rac-Enprostil

CAS: 73121-56-9

rac-Enprostil is a synthetic prostaglandin analog derived from the natural compound prostaglandin E2, produced primarily via synthetic chemical processes. This compound functions by mimicking the action of endogenous prostaglandins on the gastrointestinal mucosa. It enhances the secretion of mucus and bicarbonate, promoting mucosal protection and stability. Additionally, rac-Enprostil inhibits gastric acid secretion, thus providing a protective effect against gastric lesions and ulcers.

Formula: C₂₃H₂₈O₆

Purity: Min. 95%

Molecular weight: 400.5 g/mol

Ref: 3D-YCA12156

Enprostil

CAS: 73121-56-9

Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.

Formula: C₂₃H₂₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.46

Ref: TM-T25375