CAS 732-85-4

Leucine-β-naphthylamide

Description:

Leucine-β-naphthylamide, with the CAS number 732-85-4, is a synthetic compound that serves as a substrate for various enzymatic reactions, particularly in the study of proteases. It is an amide derivative of the amino acid leucine, which contributes to its biochemical relevance. The compound is characterized by its ability to mimic peptide bonds, making it useful in biochemical assays to evaluate enzyme activity. Leucine-β-naphthylamide is typically a white to off-white solid, and it is soluble in organic solvents, which facilitates its use in laboratory settings. Its structure includes a β-naphthyl group, which enhances its hydrophobic properties and can influence its interaction with biological molecules. In research, it is often employed in the context of studying enzyme kinetics and mechanisms, particularly in the context of proteolytic enzymes. Safety data should be consulted before handling, as with any chemical substance, to ensure proper handling and disposal procedures are followed.

Formula: C₁₆H₂₀N₂O

InChI: InChI=1S/C16H20N2O/c1-11(2)9-15(17)16(19)18-14-8-7-12-5-3-4-6-13(12)10-14/h3-8,10-11,15H,9,17H2,1-2H3,(H,18,19)/t15-/m0/s1

InChI key: InChIKey=JWHURRLUBVMKOT-HNNXBMFYSA-N

SMILES: N(C([C@H](CC(C)C)N)=O)C1=CC2=C(C=C1)C=CC=C2

Synonyms:

• (2S)-2-Amino-4-methyl-N-(naphthalen-2-yl)pentanamide
• (2S)-2-Amino-4-methyl-N-2-naphthalenylpentanamide
• <span class="text-smallcaps">L</span>-Leucine β-naphthylamide
• <span class="text-smallcaps">L</span>-Leucine-2-naphthylamide
• <span class="text-smallcaps">L</span>-Leucyl-β-naphthylamide
• H-Leu-.beta.NA
• L-Leucine Beta-Naphthylamide
• Leucine 2-naphthylamide
• Leucine-β-naphthylamide
• Leucyl-2-naphthylamide
• Leucyl-β-naphthylamide
• N-<span class="text-smallcaps">L</span>-Leucyl-2-naphthylamine
• N-naphthalen-2-yl-L-leucinamide
• N-naphthalen-2-ylleucinamide
• NCI <span class="text-smallcaps">L</span>-83633
• NSC 83633
• Pentanamide, 2-amino-4-methyl-N-2-naphthalenyl-, (2S)-
• Pentanamide, 2-amino-4-methyl-N-2-naphthalenyl-, (S)-
• Valeramide, 2-amino-4-methyl-N-2-naphthyl-, <span class="text-smallcaps">L</span>-
• Valeramide, 2-amino-4-methyl-N-2-naphthyl-, L-

H-Leu-βNA

CAS: 732-85-4

Substrate for assays of aminopeptidase M and leucine aminopeptidase. Its use for histochemical purposes has been described.

Formula: C₁₆H₂₀N₂O

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 256.35

Ref: 01-4001935

L-​Leucine-​β-​naphthylamide

CAS: 732-85-4

Formula: C₁₆H₂₀N₂O

Purity: 98%

Molecular weight: 256.3428

Ref: IN-DA00FACD

L-​Leucine-​β-​naphthylamide

Controlled Product

CAS: 732-85-4

Formula: C₁₆H₂₀N₂O

Color and Shape: Neat

Molecular weight: 256.343

Ref: TR-L330115

H-Leu-bNA

CAS: 732-85-4

H-Leu-bNA is a gene product that has been activated and is involved in the production of chronic arthritis. H-Leu-bNA is a basic protein that catalyzes the conversion of chloromethyl ketone to iodoacetic acid, which then converts neutral ph substances to acidic ph substances. This enzyme also catalyzes the conversion of amino acids to their corresponding amines and ammonia. H-Leu-bNA may be involved in autoimmune diseases with acidic phs, such as rheumatoid arthritis. It has an optimum pH of 7.4 and will not work at higher or lower pHs. The sequences for this enzyme are found in plants, but it is not found in humans or animals.br>
H-Leu-bNA can be used as a kinetic tool to measure enzyme activity. Kinetic data for this enzyme show that it has a high affinity for chloromethyl ketone and can be inhibited by certain chemicals,

Formula: C₁₆H₂₀N₂O

Purity: Min. 95%

Molecular weight: 256.34 g/mol

Ref: 3D-FL110673