CAS 73221-22-4

6-Nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine

Description:

6-Nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine is a heterocyclic organic compound characterized by its imidazo[1,2-a]pyridine core, which features a nitro group at the 6-position and a trifluoromethyl group at the 2-position. This compound is typically a yellow to orange solid, exhibiting moderate solubility in organic solvents. The presence of the nitro group contributes to its potential as an electrophile, while the trifluoromethyl group enhances its lipophilicity and may influence its biological activity. The compound is of interest in medicinal chemistry and material science due to its unique structural features, which can impart specific electronic and steric properties. Additionally, its fluorinated moiety may enhance metabolic stability and bioavailability in pharmaceutical applications. Safety data should be consulted, as compounds with nitro and trifluoromethyl groups can exhibit varying degrees of toxicity and environmental impact. Overall, 6-Nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine represents a versatile scaffold for further chemical modifications and applications in research.

Formula: C₈H₄F₃N₃O₂

InChI: InChI=1S/C8H4F3N3O2/c9-8(10,11)6-4-13-3-5(14(15)16)1-2-7(13)12-6/h1-4H

InChI key: InChIKey=CEDZYRGNBJSMSY-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CN2C(=N1)C=CC(N(=O)=O)=C2

Synonyms:

• 6-Nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine
• Imidazo[1,2-a]pyridine, 6-nitro-2-(trifluoromethyl)-