CAS 732302-99-7

Formula: C24H30ClN3O5

InChI: InChI=1S/C24H27N3O4.ClH.H2O/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30;;/h5-14,30H,3-4,15-16H2,1-2H3,(H,25,29)(H,26,28);1H;1H2

InChI key: FKGKZBBDJSKCIS-UHFFFAOYSA-N

SMILES: CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.Cl

Givinostat hydrochloride monohydrate

CAS: 732302-99-7

Givinostat hydrochloride monohydrate

Formula: C₂₄H₂₇N₃O₄·HCl·H₂O

Purity: ≥95%

Molecular weight: 475.97

Ref: 54-BUP10120

Givinostat Hydrochloride Hydrate

CAS: 732302-99-7

Formula: C₂₄H₃₀ClN₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 475.9651

Ref: IN-DA00FF97

Givinostat HCl monohydrate

CAS: 732302-99-7

(6-((Diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate hydrochloride hydrate

Formula: C₂₄H₃₀ClN₃O₅

Purity: 98%

Molecular weight: 475.97

Ref: IN-DG386438

Givinostat hydrochloride monohydrate

CAS: 732302-99-7

Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.

Formula: C₂₄H₂₇N₃O₄·HCl·H₂O

Purity: 97.97% - 99.51%

Color and Shape: White Solid

Molecular weight: 475.97

Ref: TM-T6279

Givinostat hydrochloride hydrate

CAS: 732302-99-7

Givinostat is a small molecule that inhibits autophagy, a process in which cells break down their own components. It has been shown to have dose-dependent effects on human primary cells and cell lines. Givinostat inhibits the transcriptional regulator protein complex, Toll-like receptor 4 (TLR4), and TLR4-mediated signaling pathways, which play an important role in the progression of cancer and infectious diseases. Givinostat can also be used as a therapeutic agent for colorectal adenocarcinoma in pediatric patients, with no significant side effects.

Formula: C₂₄H₂₇N₃O₄•ClH•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 475.96 g/mol

Ref: 3D-FG43357