CAS 73231-34-2

Florfenicol

Description:

Florfenicol is a synthetic antibiotic belonging to the phenicol class, primarily used in veterinary medicine for the treatment of bacterial infections in animals. It is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, making it a valuable therapeutic agent. Florfenicol functions by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the production of essential proteins necessary for bacterial growth and reproduction. The substance is characterized by its relatively low toxicity in animals compared to other antibiotics, which allows for its use in food-producing animals under regulated conditions. Florfenicol is typically administered via injection or in feed formulations, and its pharmacokinetics indicate good tissue penetration, which is beneficial for treating systemic infections. However, its use is subject to strict regulations due to concerns about antibiotic resistance and potential residues in food products. Overall, florfenicol represents an important tool in veterinary medicine, balancing efficacy against bacterial infections with considerations for safety and regulatory compliance.

Formula:C₁₂H₁₄Cl₂FNO₄S

InChI:InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)

InChI key:InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N

SMILES:[C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1

Synonyms:

2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
Aquafen
Aquaflor
Flofenicol
Flonicol
Florfeniol
Florgane
Floron
Nuflor
Sch 25298
Selectan
Topazone
Florfenicol
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
Fluorothiamphenicol
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
Sch-25298, Aquafen
(r-(r*,s*))-methyleste
2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
FLUPROFEN
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
See more synonyms

CAS 73231-34-2

Florfenicol

Florfenicol

Ref: 10-F801753