CAS 73240-30-9

Avilamycin B

Description:

Avilamycin B is a macrolide antibiotic that is primarily used in veterinary medicine, particularly for the prevention and treatment of bacterial infections in livestock. It is derived from the fermentation of the bacterium *Amycolatopsis orientalis*. Avilamycin B exhibits a broad spectrum of activity against Gram-positive bacteria, making it effective in controlling infections caused by pathogens such as *Staphylococcus* and *Streptococcus* species. The compound functions by inhibiting protein synthesis, thereby disrupting bacterial growth and replication. Its structure features a large lactone ring, characteristic of macrolides, which contributes to its biological activity. Avilamycin B is often used in feed additives to promote growth and improve feed efficiency in animals. While it is generally considered safe for use in livestock, there are regulatory considerations regarding its use in food-producing animals due to potential residues in meat and other animal products. As with any antibiotic, the development of resistance is a concern, necessitating careful management of its use in agricultural practices.

Formula: C₅₉H₈₄Cl₂O₃₂

InChI: InChI=1S/C59H84Cl2O32/c1-20-34(45(73-12)36(61)37(66)35(20)60)52(69)85-40-21(2)78-32(14-28(40)64)83-41-23(4)88-57(15-29(41)65)92-49-24(5)79-33(16-56(49,9)93-57)84-46-39(68)53(80-22(3)42(46)72-11)86-43-30(17-71-10)82-55(47(74-13)38(43)67)87-54-48(81-27(8)63)44-31(18-75-54)90-59(91-44)51-50(76-19-77-51)58(70,25(6)62)26(7)89-59/h21-24,26,28-33,38-44,46-51,53-55,64-68,70H,14-19H2,1-13H3/t21-,22-,23-,24-,26-,28-,29+,30-,31+,32+,33+,38+,39-,40-,41-,42+,43-,44-,46-,47+,48-,49-,50-,51-,53+,54+,55+,56-,57?,58+,59-/m1/s1

InChI key: InChIKey=VVIAOPGTVSECTI-OIYWUHJOSA-N

SMILES: C[C@H]1O[C@@]2([C@]3([C@]([C@@]1(C(C)=O)O)(OCO3)[H])[H])O[C@@]4([C@@](O2)(CO[C@@H](O[C@H]5[C@@H](OC)[C@@H](O)[C@H](O[C@H]6[C@H](O)[C@@H](O[C@H]7C[C@]8(C)[C@@]([C@@H](C)O7)(OC9(O8)C[C@H](O)[C@H](O[C@H]%10C[C@@H](O)[C@H](OC(=O)C%11=C(OC)C(Cl)=C(O)C(Cl)=C%11C)[C@@H](C)O%10)[C@@H](C)O9)[H])[C@@H](OC)[C@@H](C)O6)[C@@H](COC)O5)[C@@H]4OC(C)=O)[H])[H]

Synonyms:

• O-(1R)-4-C-Acetyl-6-deoxy-2,3-O-methylene-D-galactopyranosylidene-(1→3-4)-2-O-acetyl-α-L-lyxopyranosyl O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-D-arabino-hexopyranosylidene-(1→3-4)-O-2,6-dideoxy-3-C-methyl-β-D-arabino-hexopyranosyl-(1→3)-O-6-deoxy-4-O-methyl-β-D-galactopyranosyl-(1→4)-2,6-di-O-methyl-β-D-mannopyranoside
• Curamycin A
• β-D-Mannopyranoside, O-(1R)-4-C-acetyl-6-deoxy-2,3-O-methylene-D-galactopyranosylidene-(1→3-4)-2-O-acetyl-α-L-lyxopyranosyl O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-D-arabino-hexopyranosylidene-(1→3-4)-O-2,6-dideoxy-3-C-methyl-β-D-arabino-hexopyranosyl-(1→3)-O-6-deoxy-4-O-methyl-β-D-galactopyranosyl-(1→4)-2,6-di-O-methyl-
• Avilamycin B
• Flambamycin, 45-O-acetyl-45-O-de(2-methyl-1-oxopropyl)-23-deoxy-
• 45-(Acetyloxy)-45-de(2-methyl-1-oxopropyloxy)-23-deoxyflambamycin
• 45-O-Acetyl-45-O-de(1-oxo-2-methylpropyl)-23-deoxyflambamycin

Avilamycin B

CAS: 73240-30-9

Avilamycin B is an orally active antibiotic isolated from Streptomyces viridochromogenes. Avilamycin B can be utilized in research concerning diseases related to intestinal bacteria.

Formula: C₅₉H₈₄Cl₂O₃₂

Color and Shape: Solid

Molecular weight: 1376.19

Ref: TM-TN8933

Avilamycin B

CAS: 73240-30-9

Formula: C₅₉H₈₄Cl₂O₃₂

Molecular weight: 1376.19

Ref: ST-EA-CP-A224002