CAS 7332-39-0

2-(Aminomethyl)-2-(hydroxymethyl)-1,3-propanediol

Description:

2-(Aminomethyl)-2-(hydroxymethyl)-1,3-propanediol, commonly known as tris(hydroxymethyl)aminomethane or simply TRIS, is an organic compound with the molecular formula C4H11NO3. It is characterized by its three hydroxymethyl groups and an amino group, which contribute to its solubility in water and its ability to act as a buffering agent. TRIS is widely used in biochemistry and molecular biology as a buffer to maintain stable pH levels in various biochemical reactions and processes. It has a pKa value around 8.1, making it effective in the physiological pH range. The compound is typically a white crystalline solid at room temperature and is stable under normal conditions. TRIS is non-toxic and has low volatility, which makes it suitable for laboratory applications. Additionally, it is often used in the preparation of electrophoresis gels and in cell culture media. Its ability to form stable complexes with metal ions also enhances its utility in various biochemical assays.

Formula: C₅H₁₃NO₃

InChI: InChI=1S/C5H13NO3/c6-1-5(2-7,3-8)4-9/h7-9H,1-4,6H2

InChI key: InChIKey=QHQZEEGNGSZBOL-UHFFFAOYSA-N

SMILES: C(CN)(CO)(CO)CO

Synonyms:

• 2-(Aminomethyl)-2-(hydroxymethyl)-1,3-propanediol
• 1,1,1-Tris(hydroxymethyl)aminoethane
• 1,3-Propanediol, 2-(aminomethyl)-2-(hydroxymethyl)-
• 2,2,2-Tris(hydroxymethyl)ethylamine
• 2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol

2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol

CAS: 7332-39-0

2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol (DMAPP) is a plant amino acid that is an intermediate in the synthesis of aminobutyric acid. It is also involved in the synthesis of ethylene, which is important for fruit ripening. DMAPP has been shown to be a precursor for the α-subunit of carbonic anhydrase and it has been detected in urine samples and assays. The uptake of DMAPP from water by plants has been studied using gas chromatography and ultracentrifugation. DMAPP has also been used as a biochemical marker for plant physiology studies.

Formula: C₅H₁₃NO₃

Purity: Min. 95%

Molecular weight: 135.16 g/mol

Ref: 3D-HAA33239