CAS 7333-51-9

Cyclohexyltriphenylphosphonium bromide

Description:

Cyclohexyltriphenylphosphonium bromide is a quaternary ammonium salt characterized by its phosphonium cation and bromide anion. It typically appears as a white to off-white crystalline solid and is soluble in polar organic solvents. The compound features a cyclohexyl group attached to a triphenylphosphonium moiety, which contributes to its lipophilicity and stability. Cyclohexyltriphenylphosphonium bromide is often utilized in organic synthesis, particularly in reactions involving phosphonium ylides, which are key intermediates in the formation of alkenes through the Wittig reaction. Its stability under various conditions makes it a valuable reagent in synthetic chemistry. Additionally, the compound may exhibit interesting properties in biological systems, although its specific biological activity can vary based on the context of use. Safety precautions should be taken when handling this compound, as with many organophosphorus compounds, due to potential toxicity and environmental concerns.

Formula: C₂₄H₂₆P·Br

InChI: InChI=1S/C24H26P.BrH/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24;/h1-3,5-10,13-18,24H,4,11-12,19-20H2;1H/q+1;/p-1

InChI key: InChIKey=QRAKRDZMIONMRZ-UHFFFAOYSA-M

SMILES: [P+](C1CCCCC1)(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

Synonyms:

• Bromo(cyclohexyl)triphenylphosphorane
• Cyclohexyltriphenylphosphonium bromide
• Phosphonium, cyclohexyltriphenyl-, bromide
• Phosphonium, cyclohexyltriphenyl-, bromide (1:1)
• Cyclohexyltriphenylphosphonium bromide, tech. 90-95 %
• CYCLOHEXYLTRIPHENYLPHOSPHONIIUM BROMIDE
• Cyclohexyltriphenylphosphonium bromide 97%
• Cyclohexyltriphenylphosphonium bromide, 98+%

Cyclohexyltriphenylphosphonium bromide, 98+%

CAS: 7333-51-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₄H₂₆BrP

Purity: 98+%

Color and Shape: White, Powder

Molecular weight: 425.35

Ref: 02-A14298

Cyclohexyltriphenylphosphonium bromide

CAS: 7333-51-9

Formula: C₂₄H₂₆BrP

Purity: 97%

Color and Shape: Solid

Molecular weight: 425.3410

Ref: IN-DA003P5S

Cyclohexyltriphenylphosphonium bromide

CAS: 7333-51-9

Cyclohexyltriphenylphosphonium bromide

Purity: 97%

Color and Shape: Beige Solid

Molecular weight: 425.34g/mol

Ref: 54-OR6822

Cyclohexyltriphenylphosphonium bromide

CAS: 7333-51-9

Formula: C₂₄H₂₆BrP

Purity: 97%

Color and Shape: Solid

Molecular weight: 425.35

Ref: 10-F018481

Cyclohexyltriphenylphosphonium bromide

CAS: 7333-51-9

Cyclohexyltriphenylphosphonium bromide (CPTPC) is a potent nicotinic acetylcholine receptor antagonist that blocks the binding of acetylcholine to its receptor. It has been shown to have renal toxicity in rats and mice, as well as inhibition potential for nicotinic acetylcholine receptors. CPTPC binds to the carboxamido group of nicotinic acetylcholine receptors, which is situated at the outer surface of the cell membrane. The adsorption mechanism is through hydrophobic interactions with the alkyl groups on CPTPC. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit α7 nAChR activity in cells and reduce inflammatory cytokine production.

Formula: C₂₄H₂₆BrP

Purity: Min. 95%

Molecular weight: 425.34 g/mol

Ref: 3D-HAA33351