CAS 7336-40-5

N-Methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide

Description:

N-Methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide, with CAS number 7336-40-5, is a chemical compound characterized by its complex structure, which includes a tetrahydrobenzoheptalene core and multiple methoxy groups. This compound features a chiral center, indicated by the (7S) designation, which contributes to its stereochemistry and potential biological activity. The presence of the acetamide functional group suggests that it may exhibit properties typical of amides, such as hydrogen bonding capabilities. The methoxy groups can influence the compound's solubility and reactivity, potentially enhancing its pharmacological properties. Compounds of this nature are often investigated for their potential therapeutic applications, particularly in medicinal chemistry, due to their structural diversity and ability to interact with biological targets. However, specific data regarding its physical properties, such as melting point, boiling point, and solubility, would require further empirical investigation or literature reference.

Formula: C₂₃H₂₇NO₆

InChI: InChI=1/C23H27NO6/c1-13(25)24(2)17-9-7-14-11-20(28-4)22(29-5)23(30-6)21(14)15-8-10-19(27-3)18(26)12-16(15)17/h8,10-12,17H,7,9H2,1-6H3/t17-/m0/s1

InChI key: InChIKey=AHZFWPXTSZCLDJ-KRWDZBQOSA-N

SMILES: O(C)C1=C2C=3C([C@@H](N(C(C)=O)C)CCC2=CC(OC)=C1OC)=CC(=O)C(OC)=CC3

Synonyms:

• N-Methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
• N-Acetylcolchamine
• Colchicine, N-methyl-
• Acetamide, N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
• N-Methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
• Benzo[a]heptalene, acetamide deriv.
• acetamide, N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
• N-Acetaminophen
• N-Acetyldemecolcine
• N-Methylcolchicine
• NSC 403155

N-Acetyldemecolcine

CAS: 7336-40-5

N-Acetyldemecolcine

Purity: ≥98%

Molecular weight: 413.46g/mol

Ref: 54-BUP00425

N-Acetylcolchamine

CAS: 7336-40-5

Formula: C₂₃H₂₇NO₆

Purity: 95%~99%

Molecular weight: 413.47

Ref: BP-BP4542

N-Acetyldemecolcine

CAS: 7336-40-5

N-Acetaminophen (N-Methylcolchicine) is a methylated form of Colchicine.

Formula: C₂₃H₂₇NO₆

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 413.46

Ref: TM-TN7063

N-Methylcolchicine

CAS: 7336-40-5

N-Methylcolchicine is a synthetic derivative of colchicine, which is an alkaloid originally extracted from the autumn crocus plant, Colchicum autumnale. This compound acts as an antimitotic agent by disrupting the dynamics of microtubules. Specifically, N-Methylcolchicine binds to tubulin, inhibiting its polymerization into microtubules, which are crucial for chromosome segregation during cell division. This disruption arrests the cell cycle at metaphase, ultimately inhibiting cell proliferation.

Formula: C₂₃H₂₇NO₆

Purity: Min. 95%

Molecular weight: 413.50 g/mol

Ref: 3D-HAA33640