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CAS 7343-51-3

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2-[(2-Hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol

Description:
2-[(2-Hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol, commonly known as tris(hydroxymethyl)aminomethane (THAM), is an organic compound with a molecular formula of C6H15N1O3. It is characterized by its ability to act as a buffering agent, maintaining pH stability in biological and chemical systems. THAM is a white crystalline solid that is soluble in water, making it suitable for various applications in biochemistry and molecular biology. Its structure features multiple hydroxymethyl groups, which contribute to its buffering capacity, and an amino group that can participate in hydrogen bonding. This compound is often used in laboratory settings, particularly in buffer solutions for electrophoresis and cell culture. Additionally, it has low toxicity and is generally regarded as safe for use in biological applications. Its stability and effectiveness in maintaining pH make it a valuable reagent in research and clinical settings.
Formula:C6H15NO4
InChI:InChI=1S/C6H15NO4/c8-2-1-7-6(3-9,4-10)5-11/h7-11H,1-5H2
InChI key:InChIKey=OTWJRAWXTDGSDT-UHFFFAOYSA-N
SMILES:C(NCCO)(CO)(CO)CO
Synonyms:
  • 1,3-Propanediol, 2-((2-hydroxyethyl)amino)-2-(hydroxymethyl)-
  • 1,3-dihydroxy-N-(2-hydroxyethyl)-2-(hydroxymethyl)propan-2-aminium
  • 2-(2-Hydroxyethylamino)-2-hydroxymethyl-1,3-propanediol
  • 2-[(2-Hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol
  • 2-((2-Hydroxyethyl)amino)-2-(hydroxymethyl)propane-1,3-diol
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