CAS 73465-43-7

(+)-1-Deoxymannojirimycin hydrochloride

CAS: 73465-43-7

Selective inhibitor of a-mannosidase

Formula: C₆H₁₃NO₄•HCl

Molecular weight: 199.6

Ref: 02-J61277

3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-

CAS: 73465-43-7

Formula: C₆H₁₄ClNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 199.6327

Ref: IN-DA01CBEX

1-Deoxymannojirimycin hydrochloride

CAS: 73465-43-7

1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM).

Formula: C₆H₁₄ClNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 199.63

Ref: TM-T22468

1-Deoxymannojirimycin hydrochloride

CAS: 73465-43-7

1-Deoxymannojirimycin hydrochloride

Purity: >98%

Color and Shape: Solid

Molecular weight: 199.63g/mol

Ref: 54-BICL4084

1-Deoxymannojirimycin hydrochloride

CAS: 73465-43-7

Formula: C₆H₁₃NO₄HCl

Color and Shape: White to off-white powder

Molecular weight: 199.60

Ref: 7W-GA3333

Migalastat Impurity 3 HCl (Deoxymannojirimycin HCl)

CAS: 73465-43-7

Formula: C₆H₁₃NO₄·HCl

Molecular weight: 163.17 36.46

Ref: 4Z-M-249010

Deoxymannojirimycin Hydrochloride

Controlled Product

CAS: 73465-43-7

Applications Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.
References Eur. J. Biochem., 150, 41-46 (1985), J. Biol. Chem., 261, 4766 (1986), Seftor, R.E.B., et al.: Melanoma Res., 1, 43 (1991), Suzuki, S.S., et al.: J. Cell. Biochem., 51, 181 (1993)

Formula: C₆H₁₃NO₄·ClH

Color and Shape: Neat

Molecular weight: 199.63

Ref: TR-D240000

1-Deoxymannojirimycin HCl

CAS: 73465-43-7

Potent and specific inhibitor of α-mannosidase I. It is active against the Golgi isoform (GMI) of the enzyme and blocks carbohydrate branch elongation from immature to complex and hybrid N-glycans. Its anti-viral activity against HIV-1 is characterized by the alteration of N-glycan pattern and shift to high-mannose glycans on viral glycoprotein gp120, resulting in decreased infectivity of newly synthesized virions.

Formula: C₆H₁₃NO₄·HCl

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 199.63 g/mol

Ref: 3D-MD05149

3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-

CAS: 73465-43-7

Purity: 98%

Molecular weight: 199.6300049

Ref: 10-F864132