CAS 73489-90-4

Pregn-4-ene-3,20-dione hydrochloride

Description:

Pregn-4-ene-3,20-dione hydrochloride, commonly known as progesterone hydrochloride, is a synthetic derivative of the naturally occurring hormone progesterone. It is characterized by its steroid structure, which includes a four-ring core typical of steroid compounds. This substance is a white to off-white crystalline powder that is soluble in organic solvents such as ethanol and methanol but has limited solubility in water. Its molecular formula reflects the presence of a ketone group at positions 3 and 20, contributing to its biological activity. As a progestin, it plays a crucial role in regulating various physiological processes, including the menstrual cycle and pregnancy. The hydrochloride form enhances its stability and solubility, making it suitable for pharmaceutical applications. Pregn-4-ene-3,20-dione hydrochloride is primarily used in hormone replacement therapy and in the treatment of various reproductive health conditions. Safety and efficacy are well-documented, but like all medications, it may have side effects and contraindications that should be considered in clinical use.

Formula: C₂₁H₃₁ClO₂

InChI: InChI=1/C21H30O2.ClH/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3;/h12,16-19H,4-11H2,1-3H3;1H/t16-,17+,18-,19-,20-,21+;/m0./s1

Synonyms:

• (8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one hydrochloride
• Pregn-4-ene-3,20-dione hydrochloride (1:1)