CAS 735303-62-5

Benzeneacetamide, 3,4-dichloro-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-

Description:

Benzeneacetamide, 3,4-dichloro-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]- is a synthetic organic compound characterized by its complex structure, which includes a benzene ring, dichloro substituents, and an isoxazole moiety. This compound features a sulfonamide functional group, which is known for its biological activity, particularly in medicinal chemistry. The presence of the isoxazole ring contributes to its potential pharmacological properties, as isoxazoles are often associated with various biological activities, including anti-inflammatory and antimicrobial effects. The dichloro substitution on the benzene ring may enhance the compound's lipophilicity and influence its interaction with biological targets. Additionally, the sulfonamide group can participate in hydrogen bonding, which may affect the compound's solubility and reactivity. Overall, this compound's unique structural features suggest potential applications in drug development, particularly in targeting specific biological pathways. However, detailed studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₁₈H₁₅Cl₂N₃O₄S

Synonyms:

• Benzeneacetamide, 3,4-dichloro-N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-
• WAY-616763
• 2-(3,4-Dichlorophenyl)-N-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)acetamide

2-(3,4-Dichlorophenyl)-N-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)acetamide

CAS: 735303-62-5

2-(3,4-Dichlorophenyl)-N-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)acetamide

Purity: 98%

Molecular weight: 440.31g/mol

Ref: 54-OR1060757

PFK-IN-1

CAS: 735303-62-5

PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.

Formula: C₁₈H₁₅Cl₂N₃O₄S

Color and Shape: Solid

Molecular weight: 440.3

Ref: TM-T204311