CAS 7357-67-7

4-(3-chloropropyl)morpholine

Description:

4-(3-Chloropropyl)morpholine is an organic compound characterized by its morpholine ring, which is a six-membered heterocyclic structure containing one nitrogen atom and five carbon atoms. The presence of a 3-chloropropyl substituent at the 4-position of the morpholine ring introduces both a chlorine atom and a propyl chain, contributing to its chemical reactivity and potential applications. This compound is typically a colorless to pale yellow liquid with a distinctive amine-like odor. It is soluble in water and organic solvents, making it versatile for various chemical reactions. The chlorine atom in the structure can participate in nucleophilic substitution reactions, while the morpholine moiety can act as a base or nucleophile. 4-(3-Chloropropyl)morpholine is often used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, owing to its ability to serve as an intermediate in organic synthesis. Safety precautions should be taken when handling this compound, as it may pose health risks through inhalation or skin contact.

Formula: C₇H₁₄ClNO

InChI: InChI=1/C7H14ClNO/c8-2-1-3-9-4-6-10-7-5-9/h1-7H2

InChI key: InChIKey=PIAZYBLGBSMNLX-UHFFFAOYSA-N

SMILES: C(CCCl)N1CCOCC1

Synonyms:

• 1-(3-Chloropropyl)Morpholine
• 1-Chloro-3-morpholinopropane
• 3-(Morpholin-4-yl)propyl chloride
• 3-Chloro-1-(morpholin-4-yl)propane
• 3-Morpholinopropyl chloride
• Morpholine, 4-(3-chloropropyl)-
• N-(3-Chloropropyl)morpholine
• NSC 28831
• NSC 38889
• 4-(3-Chloropropyl)morpholine
• 4-(3-CHLOROPROPYL)-MORPHOLINE HYDROCHLORIDE
• N-(3-CHLOROPROPYL)MORPHOLINE HCL
• IFLAB-BB F2108-0002
• 4-(3-CHLOROPROPYL)MORPHOLINE HCL
• 4-(3-chloropropyl)-morpholin
• 3-morpholinopropylchloride
• 4-(3-CHLORO-PROPYL)-MORPHOLINE

4-(3-Chloropropyl)morpholine

CAS: 7357-67-7

Formula: C₇H₁₄ClNO

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 163.65

Ref: 3B-C2602

4-(3-Chloropropyl)morpholine, 95%

CAS: 7357-67-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₄ClNO

Purity: 95%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 163.65

Ref: 02-H35222

4-(3-Chloropropyl)morpholine

CAS: 7357-67-7

Formula: C₇H₁₄ClNO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 163.6452

Ref: IN-DA003SAV

Gefitinib Impurity 59

CAS: 7357-67-7

Formula: C₇H₁₄ClNO

Color and Shape: Colorless Liquid

Molecular weight: 163.65

Ref: 4Z-G-2315

1-Chloro-3-(morpholin-4-yl)propane

CAS: 7357-67-7

1-Chloro-3-(morpholin-4-yl)propane

Formula: C₇H₁₄ClNO

Purity: ≥95%

Color and Shape: clear. almost colourless liquid

Molecular weight: 163.65g/mol

Ref: 54-OR300520

4-(3-Chloropropyl)morpholine

Controlled Product

CAS: 7357-67-7

Applications Gefitinib intermediate.
References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),

Formula: C₇H₁₄ClNO

Color and Shape: Neat

Molecular weight: 163.65

Ref: TR-C379750

4-(3-Chloro-propyl)-morpholine

CAS: 7357-67-7

Formula: C₇H₁₄ClNO

Purity: 97%

Color and Shape: Liquid

Molecular weight: 163.65

Ref: 10-F047311

4-(3-Chloropropyl)morpholine

CAS: 7357-67-7

4-(3-Chloropropyl)morpholine is a hydrochloride salt of the potent inhibitor 4-(3-chloropropyl)morpholine. It has an inhibitory effect on cancer, and is used in chromatographic science to separate amines from aliphatic hydrocarbons. 4-(3-Chloropropyl)morpholine inhibits epidermal growth factor (EGF) and has been shown to have a potent inhibitory effect on EGF receptor tyrosine kinase activity. It also inhibits the proliferation of cells by inhibiting DNA synthesis. This compound causes cell death through the inhibition of protein synthesis, which may be due to its ability to inhibit nucleophilic reactions that are involved in protein synthesis. 4-(3-Chloropropyl)morpholine can also fluoresce under UV light, which makes it useful for research purposes.

Formula: C₇H₁₄ClNO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 163.64 g/mol

Ref: 3D-FC20377

4-(3-Chloropropyl)morpholine

CAS: 7357-67-7

Formula: C₇H₁₄ClNO

Molecular weight: 163.65

Ref: ST-EA-CP-G14015