CAS 73581-79-0

Menadione nicotinamide bisulfite

Description:

Menadione nicotinamide bisulfite, also known as vitamin K3, is a synthetic compound that combines menadione (a form of vitamin K) with nicotinamide and bisulfite. It is primarily recognized for its role in biochemical processes, particularly in the synthesis of certain proteins that are essential for blood coagulation. This compound exhibits antioxidant properties and is involved in redox reactions within biological systems. Menadione nicotinamide bisulfite is typically a yellow to orange crystalline powder, soluble in water, and has a relatively stable structure under normal conditions. It is often used in dietary supplements and fortification of food products due to its vitamin K activity. However, it is important to note that excessive intake can lead to toxicity, and its use should be monitored. The compound is also studied for its potential therapeutic applications, including its effects on cellular metabolism and its role in various health conditions.

Formula: C₁₁H₁₀O₅S·C₆H₆N₂O

InChI: InChI=1S/C11H10O5S.C6H6N2O/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;7-6(9)5-2-1-3-8-4-5/h2-5H,6H2,1H3,(H,14,15,16);1-4H,(H2,7,9)

InChI key: InChIKey=DRDSBZXTAXDLDZ-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)CC1(S(=O)(=O)O)C)=CC=CC2.C(N)(=O)C=1C=CC=NC1

Synonyms:

• 2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, compd. with 3-pyridinecarboxamide (1:1)
• 3-Pyridinecarboxamide, mono(1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate)
• Menadione nicotinamide bisulfite
• Methyl 1,4-Dioxo-1,2,3,4-Tetrahydronaphthalene-2-Sulfonate - Pyridine-3-Carboxamide (1:1)

Menadione nicotinamide bisulfite

CAS: 73581-79-0

Menadione is an inactive form of vitamin K. It is converted to the active form, menadione nicotinamide bisulfite (MK-4), by bacteria in the human gut. This conversion does not occur in animal species, and therefore MK-4 must be provided through a diet or as a supplement. Menadione nicotinamide bisulfite has been shown to be an effective treatment for vitamin K deficiency, which can lead to blood clotting problems such as coagulation disorders or sensitization. Menadione nicotinamide bisulfite functions as a cofactor in the prenylation of proteins and lipids, including clotting factors II (prothrombin), VII, IX, and X. It also participates in posttranslational modification of proteins that are important for bone metabolism.

Formula: C₁₁H₁₀O₅S·C₆H₆N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 376.38 g/mol

Ref: 3D-FM171818