CAS 73630-23-6

Quin 2

Description:

Quin 2, with the CAS number 73630-23-6, is a fluorescent chemical compound commonly used as a calcium indicator in biological and biochemical research. It belongs to the family of quinoline derivatives and is characterized by its ability to bind calcium ions, resulting in a significant change in fluorescence properties. This property makes Quin 2 particularly valuable for studying calcium dynamics in living cells, as it allows researchers to visualize and quantify intracellular calcium levels in real-time. The compound typically exhibits a high affinity for calcium, with a notable increase in fluorescence intensity upon binding. Quin 2 is often utilized in various applications, including fluorescence microscopy and flow cytometry, to monitor cellular processes influenced by calcium signaling. Its stability and sensitivity to calcium make it a preferred choice for researchers investigating calcium-related physiological and pathological processes. However, as with any chemical, proper handling and safety precautions should be observed due to potential toxicity and reactivity.

Formula: C₂₆H₂₇N₃O₁₀·4K

InChI: InChI=1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;;;

InChI key: InChIKey=MWGNREOYVRLDTL-UHFFFAOYSA-N

SMILES: N(CC(O)=O)(CC(O)=O)C=1C2=C(C=C(OC)C1)C=CC(COC3=C(N(CC(O)=O)CC(O)=O)C=CC(C)=C3)=N2.[K]

Synonyms:

• Glycine, N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-, tetrapotassium salt
• Glycine, N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-, potassium salt (1:4)
• Quin 2

Quin-2 (potassium salt)

CAS: 73630-23-6

Quin-2: fluorescent Ca^2+ indicator, Kd 115 nM; Ca^2+ selective; not Na^+, pH, or potential dependent; safe up to 2 mM; Ex/Em: 339/492 nm.

Formula: C₂₆H₂₃K₄N₃O₁₀

Color and Shape: Solid

Molecular weight: 693.87

Ref: TM-T37095